1257265-89-6

Basic information

• Product Name: 6-amino-2-((1S,3R)-1-biphenyl-4-ylmethyl-3-carboxy-butylcarbamoyl)-pyrimidine-4-carboxylic acid
• Synonyms: 6-amino-2-((1S,3R)-1-biphenyl-4-ylmethyl-3-carboxy-butylcarbamoyl)-pyrimidine-4-carboxylic acid
• CAS NO: 1257265-89-6
• Molecular Weight: 448.478
• Mol File: 1257265-89-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-amino-2-((1S,3R)-1-biphenyl-4-ylmethyl-3-carboxy-butylcarbamoyl)-pyrimidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-amino-2-((1S,3R)-1-biphenyl-4-ylmethyl-3-carboxy-butylcarbamoyl)-pyrimidine-4-carboxylic acid(1257265-89-6)
• EPA Substance Registry System: 6-amino-2-((1S,3R)-1-biphenyl-4-ylmethyl-3-carboxy-butylcarbamoyl)-pyrimidine-4-carboxylic acid(1257265-89-6)

Safety Data

• Hazardous Substances Data: 1257265-89-6(Hazardous Substances Data)

Upstream product

• 752174-62-2 (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid ethyl ester 
• 1257265-92-1 6-amino-pyrimidine-2,4-dicarboxylic acid 2-ethyl ester 
• 1257265-91-0 4-amino-6-(ethoxycarbonyl)pyrimidine-2-carboxylic acid 

Relevant articles and documents

SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS

The present invention provides a compound of formula (I') or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, X and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.