1257317-25-1

Basic information

• Product Name: N-acetyl-1,6-anhydromuramyl-L-Ala-γ-D-Glu-[N-ε-(2,4,6-trinitrophenyl)-L-lysine]
• Synonyms: N-acetyl-1,6-anhydromuramyl-L-Ala-γ-D-Glu-[N-ε-(2,4,6-trinitrophenyl)-L-lysine]
• CAS NO: 1257317-25-1
• Molecular Weight: 814.717
• Mol File: 1257317-25-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-acetyl-1,6-anhydromuramyl-L-Ala-γ-D-Glu-[N-ε-(2,4,6-trinitrophenyl)-L-lysine](CAS DataBase Reference)
• NIST Chemistry Reference: N-acetyl-1,6-anhydromuramyl-L-Ala-γ-D-Glu-[N-ε-(2,4,6-trinitrophenyl)-L-lysine](1257317-25-1)
• EPA Substance Registry System: N-acetyl-1,6-anhydromuramyl-L-Ala-γ-D-Glu-[N-ε-(2,4,6-trinitrophenyl)-L-lysine](1257317-25-1)

Safety Data

• Hazardous Substances Data: 1257317-25-1(Hazardous Substances Data)

Upstream product

• 1222520-56-0 N-acetyl-1,6-anhydromuramyl-L-Ala-γ-D-Glu-L-Lys 
• 2508-19-2 2,4,6-trinitrobenzensulfonate 

Relevant articles and documents

1,6-AnhMurNAc derivatives for assay development of amidase AmiD

Various peptidoglycan fragments were synthesized from two anhydro-muramic acid derivatives protected with a Bn or a PMB group at the 4th position, in homogenate phase or on a solid support. In order to facilitate HPLC detection, a chromophoric group was attached to the peptide chain. The periplasmic amidase sAmiD of Escherichia coli was used to cleave the amide bond between the lactyl group of the MurNAc and the α-amino group of l-Ala where the peptide chain was at least a dipeptide (l-Ala-γ-d-Glu) amidated by benzylamine on the γ-carboxyl group of d-Glu. In the presence of a tripeptide chain (l-Ala-γ-d-Glu-l-Lys) or a tetrapeptide chain (l-Ala-γ-d-Glu-m- A2pm-d-Ala) higher hydrolysis rates were observed. We have also demonstrated that the presence of TNB on the -amino group of l-Lys only has a small influence on the hydrolysis capacity of sAmiD.