125734-44-3Relevant articles and documents
Use of the Kohonen neural network for rapid screening of ex vivo anti-HIV activity of styrylquinolines
Polanski, Jaroslaw,Zouhiri, Fatima,Jeanson, Laurence,Desma?le, Didier,D'Angelo, Jean,Mouscadet, Jean-Fran?ois,Gieleciak, Rafal,Gasteiger, Johann,Le Bret, Marc
, p. 4647 - 4654 (2002)
Using the Kohonen neural network, the electrostatic potentials on the molecular surfaces of 14 styrylquinoline derivatives were drawn as comparative two-dimensional maps and compared with their known human immunodeficiency virus (HIV)-1 replication blocki
Reversing Chemoselectivity: Simultaneous Positive and Negative Catalysis by Chemically Equivalent Rims of a Cucurbit[7]uril Host
Rad, Nazar,Danylyuk, Oksana,Sashuk, Volodymyr
supporting information, p. 11340 - 11343 (2019/07/16)
Enzyme catalysis has always been an inspiration and an unattainable goal for chemists due to features such as high specificity, selectivity, and efficiency. Here, we disclose a feature neither common in enzymes nor ever described for enzyme mimics, but one that could prove crucial for the catalytic performance of the latter, namely the ability to catalyze and inhibit two different reactions at the same time. Remarkably, this can be realized by two identical, spatially resolved catalytic sites. In the future, such a synchronized catalyst action could be used not only for controlling chemoselectivity, as in the present case, but also for regulating other types of chemical reactivity.
GLUCOSE SENSOR MOLECULE
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Page/Page column 14-15, (2012/07/28)
The present invention provides a glucose sensor having a glucose receptor containing a binding site of formula (I): wherein X, n, m and R1 are defined herein. Also provided is a glucose sensor molecule for use in such a glucose sensor, the glucose sensor molecule containing the binding site of formula (I). The binding site has been found to have particularly good selectivity for glucose.