1257434-64-2Relevant articles and documents
Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling
Chen, Huifen,Volgraf, Matthew,Do, Steven,Kolesnikov, Aleksandr,Shore, Daniel G.,Verma, Vishal A.,Villemure, Elisia,Wang, Lan,Chen, Yong,Hu, Baihua,Lu, Ai-Jun,Wu, Guosheng,Xu, Xiaofeng,Yuen, Po-Wai,Zhang, Yamin,Erickson, Shawn D.,Dahl, Martin,Brotherton-Pleiss, Christine,Tay, Suzanne,Ly, Justin Q.,Murray, Lesley J.,Chen, Jun,Amm, Desiree,Lange, Wienke,Hackos, David H.,Reese, Rebecca M.,Shields, Shannon D.,Lyssikatos, Joseph P.,Safina, Brian S.,Estrada, Anthony A.
, p. 3641 - 3659 (2018)
Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed in sensory neurons where it functions as an irritant sensor for a plethora of electrophilic compounds and is implicated in pain, itch, and respiratory disease. To s
