125783-33-7

Basic information

• Product Name: N-t-butyl-3-formylandrosta-3,5-diene-17β-carboxamide
• Synonyms: N-t-butyl-3-formylandrosta-3,5-diene-17β-carboxamide
• CAS NO: 125783-33-7
• Molecular Weight: 383.574
• Mol File: 125783-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-t-butyl-3-formylandrosta-3,5-diene-17β-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-t-butyl-3-formylandrosta-3,5-diene-17β-carboxamide(125783-33-7)
• EPA Substance Registry System: N-t-butyl-3-formylandrosta-3,5-diene-17β-carboxamide(125783-33-7)

Safety Data

• Hazardous Substances Data: 125783-33-7(Hazardous Substances Data)

Upstream product

• 153002-88-1 N-[1-(3-methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17β-carboxamide 
• 153002-87-0 N-[1-(2-methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17β-carboxamide 

Downstream Products

• 119169-78-7 epristeride 

Relevant articles and documents

Steroid derivatives for the treatment of prostatic hypertrophy their preparation and uses

The invention includes compounds of formula (I): STR1 in which R1 is hydrogen, alkyl, aryl-substituted alkyl or aromatic heterocyclic-substituted alkyl; R2 is aryl-substituted alkyl, aromatic heterocyclic-substituted alkyl or diarylamino; and R3 is carboxy or a group of formula --CONHSO2 R4 wherein R4 is alkyl; and pharmaceutically acceptable salts and esters of the compounds. The compounds have valuable 5α-reductase inhibitory activity and can thus be used for the treatment and prophylaxis of, inter alia, prostatic hypertrophy as well as other disorders arising from excess levels of 5α-dihydro-testosterone.