1258208-18-2

Basic information

• Product Name: (2R)-2-[benzyl({[3-({benzyl[(2R)-1-hydroxybutane-2-yl]amino}methyl)phenyl]methyl})amino]-butane-1-ol
• Synonyms: (2R)-2-[benzyl({[3-({benzyl[(2R)-1-hydroxybutane-2-yl]amino}methyl)phenyl]methyl})amino]-butane-1-ol
• CAS NO: 1258208-18-2
• Molecular Weight: 460.66
• Mol File: 1258208-18-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R)-2-[benzyl({[3-({benzyl[(2R)-1-hydroxybutane-2-yl]amino}methyl)phenyl]methyl})amino]-butane-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-[benzyl({[3-({benzyl[(2R)-1-hydroxybutane-2-yl]amino}methyl)phenyl]methyl})amino]-butane-1-ol(1258208-18-2)
• EPA Substance Registry System: (2R)-2-[benzyl({[3-({benzyl[(2R)-1-hydroxybutane-2-yl]amino}methyl)phenyl]methyl})amino]-butane-1-ol(1258208-18-2)

Safety Data

• Hazardous Substances Data: 1258208-18-2(Hazardous Substances Data)

Upstream product

• 6257-49-4 (2R)-2-(benzylamino)butan-1-ol 
• 626-15-3 1,3-bis-(bromomethyl)benzene 

Relevant articles and documents

Chiral C2-symmetric η6-p-cymene-Ru(II)-phosphinite complexes: Synthesis and catalytic activity in asymmetric reduction of aromatic, methyl alkyl and alkyl/aryl ketones

Chiral C2-symmetric bis(phosphinite) ligands and their binuclear ruthenium(II) complexes have been synthesized and used as catalysts in the ruthenium-catalyzed asymmetric transfer hydrogenation of aromatic, methyl alkyl and alkyl/aryl ketones using 2-propanol as both the hydrogen source and solvent in the presence of KOH. Under optimized conditions, all complexes showed high catalytic activity as catalysts in the reduction of various ketones to corresponding chiral secondary alcohols. Products were obtained with high conversions (99%) and moderate to good enantioselectivities (82% ee). Furthermore, C2-symmetric bis(phosphinite) ligands and their binuclear ruthenium(II) complexes were characterized by multinuclear NMR spectroscopy, FT-IR spectroscopy, LC/MS-MS and elemental analysis.