1258274-72-4

Basic information

• Product Name: 6-chloro-7,8-dihydro-9-tritylpurine
• Synonyms: 6-chloro-7,8-dihydro-9-tritylpurine
• CAS NO: 1258274-72-4
• Molecular Weight: 398.895
• Mol File: 1258274-72-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-7,8-dihydro-9-tritylpurine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-7,8-dihydro-9-tritylpurine(1258274-72-4)
• EPA Substance Registry System: 6-chloro-7,8-dihydro-9-tritylpurine(1258274-72-4)

Safety Data

• Hazardous Substances Data: 1258274-72-4(Hazardous Substances Data)

Upstream product

• 87-42-3 6-chloropurine 
• 76-83-5 trityl chloride 

Downstream Products

• 5440-17-5 6-chloro-7-methyl-7H-purine 
• 1928-77-4 7-benzyl-6-chloro-7H-purine 
• 1258274-80-4 7-allyl-6-chloro-7,8-dihydro-9-tritylpurine 
• 1258274-85-9 6-chloro-7,8-dihydro-7-propargyl-9-tritylpurine 
• 1258274-81-5 6-chloro-7,8-dihydro-7-(3-methylbut-2-enyl)-9-tritylpurine 
• 1258274-87-1 6-chloro-7,8-dihydro-7-methyl-9-tritylpurine 

Relevant articles and documents

Selective synthesis of 7-substituted purines via 7,8-dihydropurines

A simple and efficient protocol for the preparation of 7-substituted purines is described. 6- and 2,6-Dihalopurines were N9-tritylated and then transformed to 7,8-dihydropurines by DIBAL-H. Subsequent N 7-alkylation followed by N9-trityl deprotection with trifluoroacetic acid was accompanied by spontaneous reoxidation, which led to the 7-substituted purines at 55 - 88% overall isolated yields.