1258851-07-8

Basic information

• Product Name: (+/-)-(1'S',2'S,3'R)-7-(1',3'-dihydroxy-2'-nitroindan-2'-yl)heptanoic acid
• Synonyms: (+/-)-(1'S',2'S,3'R)-7-(1',3'-dihydroxy-2'-nitroindan-2'-yl)heptanoic acid
• CAS NO: 1258851-07-8
• Molecular Weight: 323.346
• Mol File: 1258851-07-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-(1'S',2'S,3'R)-7-(1',3'-dihydroxy-2'-nitroindan-2'-yl)heptanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-(1'S',2'S,3'R)-7-(1',3'-dihydroxy-2'-nitroindan-2'-yl)heptanoic acid(1258851-07-8)
• EPA Substance Registry System: (+/-)-(1'S',2'S,3'R)-7-(1',3'-dihydroxy-2'-nitroindan-2'-yl)heptanoic acid(1258851-07-8)

Safety Data

• Hazardous Substances Data: 1258851-07-8(Hazardous Substances Data)

Upstream product

• 612-14-6 phthalyl alcohol 
• 13154-28-4 2-nitrocyclooctanone 
• 643-79-8 o-phthalic dicarboxaldehyde 

Relevant articles and documents

Two chemodivergent anionic domino processes from cyclic α-nitroketones and aromatic aldehydes

Treatment of cyclic α-nitroketones and aromatic 1,2-dialdehydes with DBU in tetrahydrofuran containing small amounts of water proceeded through two chemodivergent one-pot domino pathways, whose outcome depended on the ring size of the starting nitroketone. Thus, α-nitrocyclohexanone underwent diastereoselective α′-arylmethylenation reactions through a nitroaldol/aldol/reverse nitroaldol mechanism. On the other hand, α-nitrocycloheptanone and α-nitrocyclooctanone afforded 2-nitroindane-1,2-diols containing three contiguous stereocenters in a highly diastereoselective fashion through a nitroaldol/retro-Dieckmann/intramolecular nitroaldol process.