1259039-92-3

Basic information

• Product Name: 5-{[bis(1H-imidazol-2ylmethyl)amino]methyl}-2-[(8-cyclohexyl-2,8-diazaspiro[4.5]deca-2-yl)methyl]benzenecarboxylic acid
• Synonyms: 5-{[bis(1H-imidazol-2ylmethyl)amino]methyl}-2-[(8-cyclohexyl-2,8-diazaspiro[4.5]deca-2-yl)methyl]benzenecarboxylic acid
• CAS NO: 1259039-92-3
• Molecular Weight: 545.728
• Mol File: 1259039-92-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-{[bis(1H-imidazol-2ylmethyl)amino]methyl}-2-[(8-cyclohexyl-2,8-diazaspiro[4.5]deca-2-yl)methyl]benzenecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-{[bis(1H-imidazol-2ylmethyl)amino]methyl}-2-[(8-cyclohexyl-2,8-diazaspiro[4.5]deca-2-yl)methyl]benzenecarboxylic acid(1259039-92-3)
• EPA Substance Registry System: 5-{[bis(1H-imidazol-2ylmethyl)amino]methyl}-2-[(8-cyclohexyl-2,8-diazaspiro[4.5]deca-2-yl)methyl]benzenecarboxylic acid(1259039-92-3)

Safety Data

• Hazardous Substances Data: 1259039-92-3(Hazardous Substances Data)

Upstream product

• 78946-25-5 3-bromo-4-(bromomethyl)benzoic acid methyl ester 
• 104901-43-1 methyl 3-bromo-4-methylbenzoate 
• 7697-26-9 3-bromo-4-methylbenzoic acid 

Relevant articles and documents

COMPOUND HAVING SPIRO-BONDED CYCLIC GROUP AND USE THEREOF

The invention relates to a compound represented by formula (I): a salt thereof, an N-oxide thereof, or a solvate thereof (symbols in the formula are as described in the specification). The compound of the present invention exhibits very low risk of side effects and also has persistent and strong antagonistic activity against CXCR4, and is therefore useful as for example, preventive and/or therapeutic agent for inflammatory and immune diseases, infections (for example, HIV infection), diseases associated with HIV infection (for example, acquired immunodeficiency syndrome (AIDS)), cancer, cancer metastasis, psychoneurotic diseases and cardiovascular diseases (for example, retinopathy), metabolic diseases, cancerous diseases, or an agent for regeneration therapy.