1259519-18-0 Usage
Description
(E)-N-4-[3-chloro-4-(2-pyridinylmethoxy)aniline]-3-cyano-7-ethoxy-6-quinolinyl-4-(dimethyl-d6-amino)-2-butenamide is a complex organic compound with a unique molecular structure. It is characterized by its cyano and ethoxy substitutions on the quinolinyl moiety, as well as the presence of a dimethyl-d6-amino group on the butenamide. (E)-N-4-[3-chloro-4-(2-pyridinylmethoxy)aniline]-3-cyano-7-ethoxy-6-quinolinyl-4-(dimethyl-d6-amino)-2-butenamide is likely to have potential applications in various fields due to its structural diversity and functional groups.
Uses
Used in Pharmaceutical Industry:
(E)-N-4-[3-chloro-4-(2-pyridinylmethoxy)aniline]-3-cyano-7-ethoxy-6-quinolinyl-4-(dimethyl-d6-amino)-2-butenamide is used as an antitumor agent for the treatment of breast and non-small cell lung cancer. Its application is based on its irreversible dual EGFR/HER2 inhibitory activity, which helps in controlling the growth and progression of cancer cells.
Used in Drug Development:
In the field of drug development, this compound can be utilized as a lead molecule for the design and synthesis of novel inhibitors targeting various cancer-related proteins. Its unique structural features and functional groups make it a promising candidate for further optimization and development into more potent and selective anticancer agents.
Used in Chemical Research:
(E)-N-4-[3-chloro-4-(2-pyridinylmethoxy)aniline]-3-cyano-7-ethoxy-6-quinolinyl-4-(dimethyl-d6-amino)-2-butenamide can also be employed in chemical research to study the interactions between its functional groups and various biological targets. This may provide valuable insights into the design of new drugs with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 1259519-18-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,9,5,1 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1259519-18:
(9*1)+(8*2)+(7*5)+(6*9)+(5*5)+(4*1)+(3*9)+(2*1)+(1*8)=180
180 % 10 = 0
So 1259519-18-0 is a valid CAS Registry Number.
1259519-18-0Relevant articles and documents
SUBSTITUTED HETEROCYCLIC COMPOUNDS AS KINASES INHIBITORS AND METHOD OF USE THEREOF
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Page/Page column 34, (2011/01/12)
The present invention is directed to novel quinolines and quniazolines, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof which are useful for the treatment of protein kinases mediated diseases and conditions. The compounds of this invention have a general Formula (I) wherein R1 to R11 and X are defined herein.
