1259948-65-6

Basic information

• Product Name: (E)-3-[2-(2-bromophenyl)-2-fluorovinyl]-2-chloropyridine
• Synonyms: (E)-3-[2-(2-bromophenyl)-2-fluorovinyl]-2-chloropyridine
• CAS NO: 1259948-65-6
• Molecular Weight: 312.569
• Mol File: 1259948-65-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-[2-(2-bromophenyl)-2-fluorovinyl]-2-chloropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-[2-(2-bromophenyl)-2-fluorovinyl]-2-chloropyridine(1259948-65-6)
• EPA Substance Registry System: (E)-3-[2-(2-bromophenyl)-2-fluorovinyl]-2-chloropyridine(1259948-65-6)

Safety Data

• Hazardous Substances Data: 1259948-65-6(Hazardous Substances Data)

Upstream product

• 1259948-53-2 2-[(2-bromophenyl)fluoromethylsulfonyl]benzo[d]thiazole 
• 36404-88-3 2-chloro-3-carbaldehydepyridine 

Relevant articles and documents

Novel aromatic fluoroolefins via fluoro-Julia-Kocienski olefination

Fluoroolefins, which play an increasingly important role as peptide mimics in pharmaceuticals and as crop protection agents, are generated using a fluoro-Julia-Kocienski olefination. Their preparation can easily be accomplished using a Mitsunobu reaction and subsequent oxidation to generate the required benzothiazolyl sulfones. The key step of this process was the electrophilic -fluorination of the sulfone with N-fluorobenzenesulfonimide. The last stage of the successful synthesis of the fluoroolefins was the modified Julia-Kocienski olefination under basic conditions. Further functionalization was followed with the application of a Suzuki reaction. Georg Thieme Verlag Stuttgart.