125995-00-8 Usage
Description
(S)-(-)-3,3,3-TRIFLUORO-2-HYDROXYPROPANOIC ACID, also known as (S)-Trifluorolactic Acid, is a chiral compound with a unique structure that features a trifluoromethyl group, a hydroxyl group, and a carboxylic acid group. It is a versatile reagent in organic synthesis and has applications in various fields due to its distinctive properties.
Uses
Used in Chiral Derivatization:
(S)-(-)-3,3,3-TRIFLUORO-2-HYDROXYPROPANOIC ACID is used as a chiral derivatizing agent for alcohols, particularly in the determination of enantiomeric purity of chiral secondary alcohols. This application is crucial in the field of stereochemistry and pharmaceuticals, where the purity and composition of chiral compounds are of great importance.
Used in Synthesis of Chiral Compounds:
In the chemical industry, (S)-(-)-3,3,3-TRIFLUORO-2-HYDROXYPROPANOIC ACID serves as a reactant for synthesizing various chiral compounds, such as (S,S) Double-headed bis(trifluorolactate)s with polymethylene chains. These are produced through esterification reactions with α,ω-alkanediols, contributing to the development of new chiral materials and molecules with potential applications in various fields.
Additionally, it is utilized in the synthesis of Chiral 1,1,1-trifluoromethyl-2-alkanols, which are valuable intermediates in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. The unique properties of the trifluoromethyl group in these compounds make them attractive for various applications, including enhancing the biological activity and stability of the final products.
Check Digit Verification of cas no
The CAS Registry Mumber 125995-00-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,9,9 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 125995-00:
(8*1)+(7*2)+(6*5)+(5*9)+(4*9)+(3*5)+(2*0)+(1*0)=148
148 % 10 = 8
So 125995-00-8 is a valid CAS Registry Number.
InChI:InChI=1/C3H3F3O3/c4-3(5,6)1(7)2(8)9/h1,7H,(H,8,9)/t1-/m0/s1
125995-00-8Relevant articles and documents
Temperature-dependent penetration of argon molecules into ultramicroporous tunnel of a fluoroorganic molecular crystal with alteration of its unit cell size
Katagiri, Toshimasa,Takahashi, Satoshi,Kawabata, Koji,Hattori, Yoshiyuki,Kaneko, Katsumi,Uneyama, Kenji
, p. 504 - 505 (2006)
A molecular crystal of octamethylene (S,S)-bis(2-hydroxy-3,3,3- trifluoropropanoate) with an ultramicroporous tunnel (Φ = 2.5-2.8 A) starts to adsorb argon (Φ = 3.6 A) at 150-140 K with 7% increase of the one direction of the orthorhombic unit cell. The alteration of the unit cell size indicates the penetration of argon into the tunnel and the soft nature of the microporous molecular crystal. Copyright
