1260522-86-8

Basic information

• Product Name: methyl 6-(chloromethyl)-3-isopropoxy-2-methoxybenzoate
• Synonyms: methyl 6-(chloromethyl)-3-isopropoxy-2-methoxybenzoate
• CAS NO: 1260522-86-8
• Molecular Weight: 272.729
• Mol File: 1260522-86-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 6-(chloromethyl)-3-isopropoxy-2-methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 6-(chloromethyl)-3-isopropoxy-2-methoxybenzoate(1260522-86-8)
• EPA Substance Registry System: methyl 6-(chloromethyl)-3-isopropoxy-2-methoxybenzoate(1260522-86-8)

Safety Data

• Hazardous Substances Data: 1260522-86-8(Hazardous Substances Data)

Upstream product

• 2538-98-9 4-isopropyloxy-3-methoxybenzaldehyde 
• 1258935-43-1 (4-isopropoxy-3-methoxyphenyl)-N,N-dimethylmethanamine 
• 79-22-1 methyl chloroformate 

Downstream Products

• 1260522-87-9 methyl 3-isopropoxy-2-methoxy-6-methylbenzoate 
• 1260522-88-0 3-isopropoxy-2-methoxy-6-methylbenzoic acid 
• 1260522-89-1 3-isopropoxy-2-methoxy-6-methylbenzamide 
• 1260522-90-4 3-isopropoxy-2-methoxy-6-methylbenzonitrile 
• 1260522-91-5 C₃₅H₅₆N₂O₆SSi 
• 1260522-92-6 (S)-6-(2-amino-2-(2-(2-hydroxyethyl)-5-isopropoxy-4-methoxyphenyl)ethyl)-3-isopropoxy-2-methoxybenzonitrile 
• 1260522-93-7 (S)-3-(2-(2-hydroxyethyl)-5-isopropoxy-4-methoxyphenyl)-7-isopropoxy-8-methoxy-3,4-dihydroisoquinolin-1(2H)-one 
• 16562-14-4 (-)-stepholidine 

Relevant articles and documents

Total synthesis of (S)-(-)-stepholidine using (S)-tert-butanesulfinylimine

A new synthetic strategy of (S)-(-)-stepholidine, a promising antipsychotic drug candidate, is described. Nucleophilic addition of a laterally lithiated nitrile to a (S)-tert-butanesulfinylimine was used as the key step, which was complished in 94 % de and the main isomer was isolated in 52% yield. (S)-(-)-Stepholidine was prepared after another 5 steps, with an overall yield of 18.3% and > 98% ee. The Japan Institute of Heterocyclic Chemistry.