126065-72-3

Basic information

• Product Name: threo (+/-)-1-(acetoxymethoxy)-3-acetoxy-2-dichloroacetamido-1-p-nitrophenylpropane
• CAS NO: 126065-72-3
• Molecular Weight: 437.234
• Mol File: 126065-72-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: threo (+/-)-1-(acetoxymethoxy)-3-acetoxy-2-dichloroacetamido-1-p-nitrophenylpropane(CAS DataBase Reference)
• NIST Chemistry Reference: threo (+/-)-1-(acetoxymethoxy)-3-acetoxy-2-dichloroacetamido-1-p-nitrophenylpropane(126065-72-3)
• EPA Substance Registry System: threo (+/-)-1-(acetoxymethoxy)-3-acetoxy-2-dichloroacetamido-1-p-nitrophenylpropane(126065-72-3)

Safety Data

• Hazardous Substances Data: 126065-72-3(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 92695-77-7 cis (+/-)-4-p-nitrophenyl-5-dichloroacetamido-1,3-dioxane 
• 78021-92-8 4-phenyl-5-amino-1,3-dioxane 
• 92576-55-1 cis (+/-)-4-phenyl-5-dichloroacetamido-1,3-dioxane 

Downstream Products

• 56-75-7 threo (+/-)-2,2-dichloro-N-<2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl> acetamide 

Relevant articles and documents

REGIOSELECTIVE ACYLATIVE CLEAVAGE OF CYCLIC FORMAL OF CHLORAMPHENICOL

The amide 6 has been synthesised by reacting the amine 3 with dichloroketene in situ.This amide 6 on nitration gave formal 7, which when reacted with acetic anhydride and p-toluene sulfonic acid underwent regioselective cleavage of the dioxane ring to furnish the hemiacetal 11.This on treatment with methanol-water-ammonia yielded chloramphenicol 2.