1260830-02-1

Basic information

• Product Name: C₁₉H₁₈N₄O₃
• CAS NO: 1260830-02-1
• Molecular Weight: 350.377
• Mol File: 1260830-02-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₈N₄O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₈N₄O₃(1260830-02-1)
• EPA Substance Registry System: C₁₉H₁₈N₄O₃(1260830-02-1)

Safety Data

• Hazardous Substances Data: 1260830-02-1(Hazardous Substances Data)

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 129886-28-8 1-(3-Methyl-2(1H)-quinoxalinonyl)acetic acid hydrazide 
• 99-93-4 4-Hydroxyacetophenone 
• 129886-27-7 ethyl 2-(3-methyl-2-oxo-1,2-dihydroquinoxalin-1-yl)acetate 
• 14003-34-0 3-methyl-2-oxo-1,2-dihydroquinoxaline 

Relevant articles and documents

Synthesis and biological evaluation of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)-N'-(substituted phenylmethyledene/ethylidene)acetohydrazides

A series of quinoxaline derivatives was prepared and evaluated for antitubercular, antibacterial and antifungal activities. The title compounds were prepared by condensation of substituted aromatic aldehydes and substituted acetophenones with 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl) acetohydrazide. Structures of all these compounds were confirmed by their spectral studies. Among synthesized compounds (4r, 4t, 4u, 4w and 4x) have shown good anti tubercular activity (25 μg mL-1) when compared to reference drugs pyrazinamide (10 μg mL-1) and streptomycin (7.5 μg mL-1). In this study, few derivatives showed broad spectrum of antimicrobial activity at low concentration. The MICs (Minimum inhibitory concentration) of some compounds are 2-4 μg mL-1.