126093-00-3

Basic information

• Product Name: 1H-Pyrrole-2-carboxylic acid, 4-[[[4-[[[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-methyl-1H-pyrrol-2-yl] carbonyl]amino]-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-, methyl ester
• CAS NO: 126093-00-3
• Molecular Formula: C24H30N6O6
• Molecular Weight: 498.539
• Mol File: 126093-00-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-2-carboxylic acid, 4-[[[4-[[[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-methyl-1H-pyrrol-2-yl] carbonyl]amino]-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2-carboxylic acid, 4-[[[4-[[[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-methyl-1H-pyrrol-2-yl] carbonyl]amino]-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-, methyl ester(126093-00-3)
• EPA Substance Registry System: 1H-Pyrrole-2-carboxylic acid, 4-[[[4-[[[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-methyl-1H-pyrrol-2-yl] carbonyl]amino]-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-, methyl ester(126093-00-3)

Safety Data

• Hazardous Substances Data: 126093-00-3(Hazardous Substances Data)

Usage

1H-Pyrrole-2-carboxylic acid

A five-membered aromatic ring with a carboxyl group attached to the second carbon.

Methyl ester derivative

The carboxyl group is esterified with a methyl group.

Multiple repeating units

The molecule contains multiple repeating units of 1-methyl-1H-pyrrol-2-yl carbonyl amino groups.

Pyrrole and carboxylic acid functional groups

The molecule contains both pyrrole and carboxylic acid functional groups, which are important for its reactivity and potential biological activity.

Applications in scientific and medical fields

Due to its intricate molecular structure, this chemical may have applications in various scientific and medical fields, including drug development and organic synthesis.

Upstream product

• 67-56-1 methanol 
• 77716-11-1 4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrrole-2-carboxylic acid 
• 126092-97-5 methyl 4-<<<4-<<(tert-butyloxy)carbonyl>amino>-1-methyl-pyrrol-2-yl>carbonyl>amino>-1-methyl-pyrrole-2-carboxylate 
• 126092-99-7 methyl 4-(4-amino-1-methyl-1H-pyrrole-2-carboxamido)-1-methyl-1H-pyrrole-2-carboxylate 

Downstream Products

• 1312790-32-1 4-{4-[4-(3-carboxybenzamido)-1-methyl-1H-pyrrole-2-carboxamido]-1-methyl-1H-pyrrole-2-carboxamido}-1-methyl-1H-pyrrole-2-carboxylic acid 
• 1312790-30-9 methyl 4-(4-{4-[3-(methoxycarbonyl)benzamido]-1-methyl-1H-pyrrole-2-carboxamido}-1-methyl-1H-pyrrole-2-carboxamido)-1-methyl-1H-pyrrole-2-carboxylate 
• 126093-05-8 (5-{5-[5-({[4-(Acridin-9-ylamino)-phenylcarbamoyl]-methyl}-carbamoyl)-1-methyl-1H-pyrrol-3-ylcarbamoyl]-1-methyl-1H-pyrrol-3-ylcarbamoyl}-1-methyl-1H-pyrrol-3-yl)-carbamic acid tert-butyl ester 
• 65361-29-7 C₂₄H₃₂N₈O₄ 

Relevant articles and documents

METHOD FOR PRODUCING NITROGEN-CONTAINING AROMATIC AMIDE, METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE, AND COMPOUND

To provide a method for producing a nitrogen-containing aromatic amide that is capable of using a monomer unit obtained under milder reaction condition and uses catalytic amide bond formation, and a method for producing a pyrrole-imidazole polyamide. [1] A method for producing a nitrogen-containing aromatic amide, including reacting a compound 1 represented by the general formula (1) and a compound 2 represented by the general formula (2) in the presence of a transition metal catalyst and a base, so as to provide a compound 3 represented by the general formula (3). [2] A method for producing a pyrrole-imidazole polyamide, including using the compound 3 obtained by the production method according to the item [1]. [3] A compound represented by the general formula (2aa), the general formula (2ab), the general formula (2ac), or the general formula (2ad).

A modular synthetic route to dimeric calixarenes: A new family of DNA major groove binders

We describe here a general strategy for the synthesis of dimeric anilinium/guanidinium calix[4]arenes with aliphatic and heteroaromatic bridges. These compounds display a remarkably high affinity towards double-stranded (ds) DNA and act by a rare mechanism, i.e., insertion into the wide major groove of the nucleic acids. Georg Thieme Verlag Stuttgart New York.

ALKYL 4- [4- (5-OXO-2, 3, 5, 11A-TETRAHYD0-5H-PYRR0L0 [2, 1-C] [1, 4] BENZODIAZEPINE-8-YLOXY) -BUTYRYLAMINO]-1H-PYRROLE-2-CARBOXYLATE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF A PROLIFERATIVE DISEASE

A compound of formula (I); or a salt or solvate thereof, wherein: the dotted line indicates the optional presence of a double bond between C2 and C3; R2 is selected from -H, -OH, =0, =CH2, -CN, -R, OR, halo, =CH-R, O-SO2-R, CO2R and COR; R7 is selected from H, R, OH, OR, SH, SR, NH2, NHR, NRR', nitro, Me3Sn and halo, where R and R' are independently selected from optionally substituted C1-7 alkyl, C3-20 heterocyclyl and C5-20 aryl groups; R10 and R11 either together form a double bond, or are selected from H and YRY, where Y is selected from O, S and NH and RY is H or C1-7 alkyl or H and SOxM, where x is 2 or 3, and M is a monovalent pharmaceutically acceptable cation; each X is independently a heteroarylene group; n is from 1 to 6; and RE is C1-4 alkyl. The compound is useful for the treatment of proliferative diseases.