1261061-27-1Relevant articles and documents
A general and practical access to chiral quinoxalinones with low copper-catalyst loading
Tanimori, Shinji,Kashiwagi, Hiroaki,Nishimura, Takeshi,Kirihata, Mitsunori
scheme or table, p. 2531 - 2537 (2010/12/29)
A general, straightforward, and practical access to multi-substituted chiral quinoxalin-2-ones has been achieved based on the copper(I) chloride-dimethylethylenediamine (DMEDA) catalyst system. With the use of 1 mol% copper(I) chloride, structurally diverse quinoxalin-2-ones were generated with high optical purity from readily available starting materials, 2-haloanilines and α-amino acids, in a one-pot manner.