1261084-18-7Relevant articles and documents
Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors
Ahonen, Tiina J.,Rinne, Maiju,Grutschreiber, Peter,M?tlik, Kert,Airavaara, Mikko,Schaarschmidt, Dieter,Lang, Heinrich,Reiss, David,Xhaard, Henri,Gaveriaux-Ruff, Claire,Yli-Kauhaluoma, Jari,Moreira, Vania M.
, p. 495 - 507 (2018/04/14)
Despite extensive years of research, the direct oxidation of the 7,8-double bond of opioids has so far received little attention and knowledge about the effects of this modification on activity at the different opioid receptors is scarce. We herein report