1261254-48-1

Basic information

• Product Name: 17β-Estradiol-[2,3,4-13C3]
• Synonyms: 17β-Estradiol-[2,3,4-13C3];17β-Estradiol-[2,3,4-13C3] (CertiMass solution);17β-Estradiol-2,3,4-13C3 solution
• CAS NO: 1261254-48-1
• Molecular Weight: 0
• EINECS: 200-835-2
• Mol File: 1261254-48-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 17β-Estradiol-[2,3,4-13C3](CAS DataBase Reference)
• NIST Chemistry Reference: 17β-Estradiol-[2,3,4-13C3](1261254-48-1)
• EPA Substance Registry System: 17β-Estradiol-[2,3,4-13C3](1261254-48-1)

Safety Data

• Hazardous Substances Data: 1261254-48-1(Hazardous Substances Data)

Usage

Labeled form

Contains three carbon-13 isotopes at positions 2, 3, and 4 of the estradiol molecule.

Hormone type

A type of estrogen hormone.

Tracking and identification

Allows for tracking and identification in biological and chemical systems using nuclear magnetic resonance (NMR) and mass spectrometry techniques.

Involvement in female reproductive system

Regulates the female reproductive system.

Functions

Plays a role in the menstrual cycle, pregnancy, and development of secondary sexual characteristics.

Scientific research

Utilized in scientific research for studying estrogen metabolism and hormone-related diseases.

Medical diagnostics

Used in medical diagnostics for studying hormone-related diseases such as breast cancer and osteoporosis.

Upstream product

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• 41878-34-6 (1S,7aS)-1-tert-Butoxy-4-(3,3-dimethoxy-butyl)-7a-methyl-1,2,3,6,7,7a-hexahydro-inden-5-one 
• 41878-32-4 1β-t-butoxy-4-(3'-oxobutyl)-7aβ-methyl-7,7a-dihydro-5(6H)-indanone 
• 41878-35-7 (3S,3aS)-3-tert-Butoxy-7-methoxy-3a,7-dimethyl-2,3,3a,4,5,7,8,9-octahydro-6-oxa-cyclopenta[a]naphthalene 
• 41878-36-8 (3S,3aS,9bR)-3-tert-Butoxy-7-methoxy-3a,7-dimethyl-1,2,3,3a,4,5,7,8,9,9b-decahydro-6-oxa-cyclopenta[a]naphthalene 
• 101025-39-2 (1S,3aS,7aS)-1-tert-Butoxy-7a-methyl-4-(3-oxo-butyl)-octahydro-inden-5-one 
• 41878-38-0 (1S,7aS)-1-tert-butoxy-7a-methyl-1,2,3,6,7,7a-hexahydro-5H-inden-5-one 
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• 101025-44-9 C₁₈⁽¹³⁾C₄H₃₂O₂ 

Relevant articles and documents

[1,2,3,4-13C] testosterone and [1,2,3,4-13C] estradiol

The preparation of [1,2,3,4-13C] testosterone and of [1,2,3,4-13C] estradiol by total synthesis is described. The 13C labels are introduced by alkylating intermediate 1 with [1,2,3,4-13C]l-iodo-3,3-ethylenedioxybutane (2) to obtain intermediate 10. Hydrolysis of the ketal function, cyclization, aromatization and removal of protective groups gave [1,2,3,4-13C] estradiol. Labeled testosterone was prepared by methylating intermediate 10 and by subsequent treatment with acid. The labeled steroids can be used as tracers for in vivo metabolic studies and as internal standards for the development of definitive gc-ms quantitative methods.