1261826-46-3Relevant articles and documents
Synthesis of Indole-Fused Polycyclics via Rhodium-Catalyzed Undirected C-H Activation/Alkene Insertion
Guo, Songjin,Pan, Rui,Guan, Zhe,Li, Panpan,Cai, Libo,Chen, Siwei,Lin, Aijun,Yao, Hequan
supporting information, p. 6320 - 6324 (2019/08/26)
A Rh(III)-catalyzed undirected C-H activation/alkene insertion to synthesize diversified indole-fused polycyclics has been developed. Intramolecular electrophilic cyclization generated a 3-indolyl rhodium species that went through an aryl-to-aryl 1,4-rhodium migration to realize the C-H activation. The subsequent [4 + 2] carboannulation or hydroarylation of alkenes could be achieved, respectively, by simply adjusting the additives of the reaction.
Sterically controlled iodination of arenes via iridium-catalyzed C-H borylation
Partridge, Benjamin M.,Hartwig, John F.
supporting information, p. 140 - 143 (2013/03/28)
A mild method to prepare aryl and heteroaryl iodides by sequential C-H borylation and iodination is reported. The regioselectivity of this process is controlled by steric effects on the C-H borylation step and is complementary to existing methods to form aryl iodides. The iodination of boronic esters has potential for the synthesis of radiolabeled aryl iodides, as demonstrated by the concise synthesis of a potential tracer for SPECT imaging.
