1262030-04-5

Basic information

• Product Name: dimethyl 1-(2-methoxy-2-oxoethyl)-4,5-dihydro-1H-pyrazole-3,5-dicarboxylate
• Synonyms: dimethyl 1-(2-methoxy-2-oxoethyl)-4,5-dihydro-1H-pyrazole-3,5-dicarboxylate
• CAS NO: 1262030-04-5
• Molecular Weight: 258.231
• Mol File: 1262030-04-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl 1-(2-methoxy-2-oxoethyl)-4,5-dihydro-1H-pyrazole-3,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 1-(2-methoxy-2-oxoethyl)-4,5-dihydro-1H-pyrazole-3,5-dicarboxylate(1262030-04-5)
• EPA Substance Registry System: dimethyl 1-(2-methoxy-2-oxoethyl)-4,5-dihydro-1H-pyrazole-3,5-dicarboxylate(1262030-04-5)

Safety Data

• Hazardous Substances Data: 1262030-04-5(Hazardous Substances Data)

Upstream product

• 6832-16-2 methyl diazoacetate 
• 292638-85-8 acrylic acid methyl ester 

Relevant articles and documents

Reactions of diazo esters with electron-deficient alkenes in the presence of Lewis acids

1,3-Dipolar cycloaddition reaction of diazo esters to electron-deficient dipolarophiles to yield the corresponding 1- or 2-pyrazolines was found to be significantly accelerated with Lewis acids (Yb(OTf)3, Sc(OTf) 3, GaCl3, EtAlCl2). The use of GaCl3 as the catalyst leads to the acceleration not only of the 1,3-dipolar cycloaddition reaction, but also subsequent insertion of the CHCO2Me electrophilic fragment of methyl diazoacetate into the N-H bond of 2-pyrazolines formed. Such Lewis acids as SnCl4, BF3, TiCl4, and In(OTf)3 are not efficient in the described processes, since they rapidly decompose starting diazo compounds.