1262030-16-9Relevant articles and documents
METHODS OF MAKING EFAVIRENZ AND INTERMEDIATES THEREOF
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Page/Page column 12, (2011/02/18)
The present invention provides a process for the preparation of Efavirenz. A compound of Formula 1 may be prepared by a process comprising cyclizing, in the presence of a first base, a compound of Formula 5 with a haloformate of Formula 6. Other processes are also provided as well as novel compounds prepared by and used in such processes.