1262133-64-1

Basic information

• Product Name: 3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine
• Synonyms: 3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine;CAPECITABINE related substance USP;5'-Deoxy-3'-O-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-N-[(pentyloxy)carbonyl]cytidine;Capecitabine USP IMp.G;3'-(5'-Deoxy-Beta-D-ribofuranoyl) Capecitabine;Cytidine, 5'-deoxy-3'-O-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-N-[(pentyloxy)carbonyl]-;pentyl (1-((2R,3R,4S,5R)-4-(((2S,3R,4S,5R)-3,4-dihydroxy-5-methyl tetra hydrofuran-2-yl)oxy)-3-hydroxy-5-methyltetra hydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate;Capecitabine impurity G
• CAS NO: 1262133-64-1
• Molecular Formula: C20H30FN3O9
• Molecular Weight: 475.4653032
• Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Impurities;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
• Mol File: 1262133-64-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.57±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 5.40±0.40(Predicted)
• CAS DataBase Reference: 3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine(1262133-64-1)
• EPA Substance Registry System: 3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine(1262133-64-1)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 1262133-64-1(Hazardous Substances Data)

Usage

Description

3'-O-(5'-Deoxy-α-D-ribofuranosyl) capecitabine, also known as Capecitabine 3-O-BDR Impurity, is a derivative of capecitabine, an oral chemotherapy drug. It is a white to off-white solid and is used as an impurity in the production and quality control of capecitabine. 3'-O-(5'-Deoxy-α-D-ribofuranosyl) capecitabine plays a significant role in ensuring the purity and efficacy of capecitabine, which is a crucial factor in its therapeutic applications.

Uses

Used in Pharmaceutical Industry:
3'-O-(5'-Deoxy-α-D-ribofuranosyl) capecitabine is used as an impurity in the production of capecitabine (C175650) for ensuring the quality and purity of the final drug product. Its presence is essential for maintaining the safety and efficacy of capecitabine, which is used in the treatment of various types of cancer.
Used in Quality Control:
3'-O-(5'-Deoxy-α-D-ribofuranosyl) capecitabine is used as a reference standard in the quality control processes of capecitabine manufacturing. It helps in the identification, quantification, and assessment of impurities in the final drug product, ensuring that the capecitabine meets the required standards for therapeutic use.
Used in Research and Development:
3'-O-(5'-Deoxy-α-D-ribofuranosyl) capecitabine is also used in research and development for studying the chemical properties, stability, and interactions of capecitabine. This information is crucial for the development of new formulations, drug delivery systems, and potential improvements in the therapeutic applications of capecitabine.