1262133-66-3

Basic information

• Product Name: 2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine
• Synonyms: 2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine;[1-[5'-Deoxy-2-O-(5'-deoxy-β-D-ribofuranosyl)-β-D-ribofuranosyl]-5-fluoro-2-oxo-1,2-dihydropyriMidin-4-yl]carbaMic Acid Pentyl Ester;5'-Deoxy-2'-O-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-N-[(pentyloxy)carbonyl]cytidine;2'-O-(5'-Deoxy-2,3-diacetyl-β-D-ribofuranosyl) Capecitabine 3-Benzoate;Capecitabine USP IMp.H;2'-(5'-Deoxy-Beta-D-ribofuranoyl) Capecitabine;Cytidine, 5'-deoxy-2'-O-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-N-[(pentyloxy)carbonyl]-;Capecitabine Impurity L
• CAS NO: 1262133-66-3
• Molecular Formula: C31H38FN3O12
• Molecular Weight: 663.6447232
• Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Impurities;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
• Mol File: 1262133-66-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 80-82°C
• Appearance: /
• Density: 1.57±0.1 g/cm3(Predicted)
• Storage Temp.: -20?C Freezer
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 5.38±0.40(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: 2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine(1262133-66-3)
• EPA Substance Registry System: 2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine(1262133-66-3)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 1262133-66-3(Hazardous Substances Data)

Usage

Description

2'-O-(5'-Deoxy-β-D-ribofuranosyl) capecitabine, also known as Capecitabine 2-O-BDR Impurity, is a derivative of capecitabine, an oral chemotherapy drug. It is a white to off-white solid and is used as an impurity in the production and quality control of capecitabine. 2'-O-(5'-Deoxy-β-D-ribofuranosyl) capecitabine plays a significant role in ensuring the purity and efficacy of capecitabine, which is crucial for its therapeutic applications.

Uses

Used in Pharmaceutical Industry:
2'-O-(5'-Deoxy-β-D-ribofuranosyl) capecitabine is used as an impurity in the production of capecitabine for the following reasons:
It helps in maintaining the quality and purity of capecitabine, ensuring that the final product meets the required standards for safety and efficacy.
As an impurity, it aids in the development of analytical methods for the identification, quantification, and control of impurities in capecitabine, which is essential for regulatory compliance and patient safety.
Used in Quality Control:
2'-O-(5'-Deoxy-β-D-ribofuranosyl) capecitabine is used as a reference material in quality control processes for the following reasons:
It provides a benchmark for the identification and quantification of impurities in capecitabine, allowing for accurate assessment of product quality.
As a reference material, it helps in the development and validation of analytical methods, ensuring the reliability and reproducibility of test results.
Used in Research and Development:
2'-O-(5'-Deoxy-β-D-ribofuranosyl) capecitabine is used as a research compound for the following reasons:
It serves as a valuable tool for understanding the chemical properties and behavior of capecitabine and its related compounds, which can lead to the development of improved formulations or new therapeutic agents.
As a research compound, it can be used to study the mechanisms of action, metabolism, and potential side effects of capecitabine, contributing to a better understanding of its therapeutic potential and safety profile.