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1262152-85-1

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1262152-85-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1262152-85-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,1,5 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1262152-85:
(9*1)+(8*2)+(7*6)+(6*2)+(5*1)+(4*5)+(3*2)+(2*8)+(1*5)=131
131 % 10 = 1
So 1262152-85-1 is a valid CAS Registry Number.

1262152-85-1Downstream Products

1262152-85-1Relevant articles and documents

The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia

Ho, Ginny D.,Michael Seganish,Bercovici, Ana,Tulshian, Deen,Greenlee, William J.,Van Rijn, Rachel,Hruza, Alan,Xiao, Li,Rindgen, Diane,Mullins, Deborra,Guzzi, Mario,Zhang, Xiaoping,Bleickardt, Carina,Hodgson, Robert

, p. 2585 - 2589 (2012/05/05)

The identification of potent and orally active dihydroimidazoisoquinolines as PDE 10A inhibitors is reported. The SAR development led to the discovery of compound 35 as a potent, selective, and orally active PDE10A inhibitor. Compound 35 inhibited MK-801-induced hyperactivity at 3 mg/kg and displayed a 10-fold separation between the minimal effective doses for inhibition of MK-801-induced hyperactivity and hypolocomotion in rats.

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