126254-87-3

Basic information

• Product Name: (S)-2,3-dihydroxypropyl butyrate
• Synonyms: (S)-2,3-dihydroxypropyl butyrate
• CAS NO: 126254-87-3
• Molecular Weight: 162.186
• Mol File: 126254-87-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2,3-dihydroxypropyl butyrate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2,3-dihydroxypropyl butyrate(126254-87-3)
• EPA Substance Registry System: (S)-2,3-dihydroxypropyl butyrate(126254-87-3)

Safety Data

• Hazardous Substances Data: 126254-87-3(Hazardous Substances Data)

Upstream product

• 2461-40-7 (+/-)-glycidyl butyrate 

Downstream Products

• 744198-92-3 (2R)-3-(phenylseleno)propane-1,2-diol 
• 702711-08-8 (2R)-2-hydroxy-3-(phenylseleno)propylbutyrate 

Relevant articles and documents

Stereoselective synthesis of (R)-glycidyl butyrate from racemic glycidyl butyrate or epichlorohydrin via hydrolytic kinetic resolution

The differences of (R)-glycidyl butyrate synthesis via hydrolytic kinetic resolution of glycidyl butyrate directly or regioselective opening epichlorohydrin as key steps by using Jacobsen's hydrotic kinetic resolution are compared. In the view of separation problem, it is hard to get the pure (R)-glycidyl butyrate by kinetic resolution of glycidyl butyrate directly. Via kinetic resolution of epichlorohydrin, treatment with butyric acid in the presence of CrCl3 and then epoxidation with NaOH, the total yield of 38.5% and optical purity of 99% are obtained.