126267-63-8

Basic information

• Product Name: 2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine
• Synonyms: 2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine
• CAS NO: 126267-63-8
• Molecular Formula: C₁₃H₉N₃O₂
• Molecular Weight: 239.22946
• Mol File: 126267-63-8.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine(126267-63-8)
• EPA Substance Registry System: 2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine(126267-63-8)

Safety Data

• Hazardous Substances Data: 126267-63-8(Hazardous Substances Data)

Usage

Description

2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine is a heterocyclic chemical compound characterized by the molecular formula C12H8N4O2. It features a nitrophenyl group attached to an imidazo-pyridine ring structure, which endows it with unique chemical properties. 2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine is primarily utilized in research and pharmaceutical applications, making it a significant target for medicinal chemistry and drug development due to its potential therapeutic applications.

Uses

Used in Pharmaceutical Research and Development:
2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine is used as a research compound for exploring its potential as a therapeutic agent. It is being studied for its possible applications in treating various conditions, such as cancer and neurological disorders, due to its unique chemical structure and properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine serves as a key compound for investigating its interactions with biological targets. Its structure allows for the design and synthesis of new drug candidates that can modulate specific biological pathways, offering potential treatments for a range of diseases.
Used in Materials Science:
2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine also has potential applications in materials science. Its unique molecular structure can be leveraged to develop new materials with specific properties, such as optical, electronic, or mechanical characteristics, which can be utilized in various industries.
Used in Organic Synthesis:
In organic synthesis, 2-(2-nitrophenyl)H-iMidazo[1,2-a]pyridine can be employed as a building block or intermediate in the synthesis of more complex organic molecules. Its reactivity and functional groups make it a valuable component in the creation of novel compounds with diverse applications.

Upstream product

• 504-29-0 2-aminopyridine 
• 6851-99-6 2-bromo-1-(2-nitrophenyl)ethanone 
• 253684-24-1 1-(2,2-dibromovinyl)-2-nitrobenzene 
• 110-86-1 pyridine 
• 1562372-97-7 C₁₀H₉N₅O₂ 
• 552-89-6 2-nitro-benzaldehyde 
• 577-59-3 2-acetylnitrobenzene 
• 4105-21-9 2-phenylimidazo[1,2-a]pyridine 
• 10342-62-8 1-(2-nitro-phenyl)-ethanone oxime 

Downstream Products

• 126267-64-9 2-(2-nitrophenyl)-3-nitrosoimidazo(1,2-a)pyridine 
• 126267-67-2 (2-Amino-phenyl)-[(Z)-pyridin-2-ylimino]-acetonitrile 
• 126267-66-1 2-(2-aminophenyl)-3-aminoimidazo(1,2-a)pyridine 
• 126267-69-4 2-(2-Amino-phenyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-3-ylamine 
• 126267-65-0 2-(2-Nitro-phenyl)-imidazo[1,2-a]pyridin-3-ylamine 
• 126267-70-7 3-((N-2-chlorobenzylidene)-amino)-2-imidazo(1,2-a)pyridinyl-2,2'-aminobenzene 
• 126267-71-8 6-(2-chlorophenyl)pyrido(1',2':1,2)imidazo(5,4-d)(1.3)benzodiazepine 
• 1621431-71-7 6-phenylpyrido[2′,1′:2,3]imidazo[4,5-c]quinoline 
• 945933-92-6 6-(4-nitrophenyl)pyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 1621431-72-8 6-(4-fluorophenyl)pyrido[2′,1′:2,3]imidazo[4,5-c]quinoline 
• 1621431-73-9 6-(4-methoxyphenyl)pyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 945933-96-0 6-methyl-6-phenyl-5,6-dihydropyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 945933-99-3 6-methyl-6-(4-nitrophenyl)-5,6-dihydropyrido[2',1':2,3]imidazo[4,5-c]quinoline 
• 945933-98-2 6-(4-methoxyphenyl)-6-methyl-5,6-dihydropyrido[2',1':2,3]imidazo[4,5-c]quinoline 

Relevant articles and documents

An expeditious microwave assisted one-pot sequential route to pyrido fused imidazo[4,5-c] quinolines in green media

An expeditious microwave assisted one-pot sequential route to synthesize pyrido fused imidazo[4,5-c]quinolinesviathe Pictet-Spengler cyclization strategy has been developed. In this study, substituted 2-amino pyridines are condensed with 2-bromo-2′-nitroa

CuCl2-catalyzed N[sbnd]O bond cleavage of oxime esters: Approach to imidazoheterocycles and furo[3,2-c]chromenyl fused imidazoles

An articulate approach to a diverse set of imidazoheterocycles in good to high yields via a copper-catalyzed aza-annulation of several oxime esters with a group of 2-amino-azaarenes was developed. The above cyclization reaction probably proceeds via a single electron transfer process which embodies a new technique for creating two new C[sbnd]N bonds for imidazole ring synthesis. Gratifyingly, the implementation of this chemistry could be further stretched to the synthesis of a novel class of fused imidazoles bearing a furo[3,2-c]chromene moiety via a sequential C[sbnd]N bond formation, followed by C(sp2)-H functionalization/5-endo-dig-oxacyclization (C[sbnd]C and C[sbnd]O bonds) of in situ produced fused imidazoles with cyclic enynones in the presence of copper(II) as a π-electrophilic Lewis acid catalyst.

Efficient Access to Imidazo[1,2- a] pyridines/pyrazines/pyrimidines via Catalyst-Free Annulation Reaction under Microwave Irradiation in Green Solvent

An expeditious catalyst-free heteroannulation reaction for imidazo[1,2-a]pyridines/pyrimidines/pyrazines was developed in green solvent under microwave irradiation. Using H2O-IPA as the reaction medium, various substituted 2-aminopyridines/pyra