1262847-67-5

Basic information

• Product Name: N-((R)-1-carbamoylethyl)-3-{5-[4-(4-methylpiperazin-1-yl)phenyl]isoxazol-3-yl}benzamide
• Synonyms: N-((R)-1-carbamoylethyl)-3-{5-[4-(4-methylpiperazin-1-yl)phenyl]isoxazol-3-yl}benzamide
• CAS NO: 1262847-67-5
• Molecular Weight: 433.51
• Mol File: 1262847-67-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-((R)-1-carbamoylethyl)-3-{5-[4-(4-methylpiperazin-1-yl)phenyl]isoxazol-3-yl}benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((R)-1-carbamoylethyl)-3-{5-[4-(4-methylpiperazin-1-yl)phenyl]isoxazol-3-yl}benzamide(1262847-67-5)
• EPA Substance Registry System: N-((R)-1-carbamoylethyl)-3-{5-[4-(4-methylpiperazin-1-yl)phenyl]isoxazol-3-yl}benzamide(1262847-67-5)

Safety Data

• Hazardous Substances Data: 1262847-67-5(Hazardous Substances Data)

Upstream product

• 1284211-19-3 C₂₁H₂₁N₃O₃ 
• 35320-22-0 D-alaninamide 
• 1262847-54-0 3-{5-[4-(4-methylpiperazin-1-yl)phenyl]isoxazol-3-yl}benzoic acid methyl ester 
• 1262847-52-8 3-[5-(4-bromophenyl)isoxazol-3-yl]benzoic acid methyl ester 
• 1262847-45-9 3-[5-(4-bromophenyl)isoxazol-3-yl]benzoic acid 
• 766-96-1 4-bromo-1-ethynylbenzene 

Downstream Products

• 1262845-96-4 N-((R)-cyano-methyl-methyl)-3-{5-[4-(4-methylpiperazin-1-yl)phenyl]isoxazol-3-yl}benzamide 

Relevant articles and documents

3,5-Diarylazoles as novel and selective inhibitors of protein kinase D

The synthesis and preliminary studies of the SAR of novel 3,5-diarylazole inhibitors of Protein Kinase D (PKD) are reported. Notably, optimized compounds in this class have been found to be active in cellular assays of phosphorylation-dependant HDAC5 nuclear export, orally bioavailable, and highly selective versus a panel of additional putative histone deacetylase (HDAC) kinases. Therefore these compounds could provide attractive tools for the further study of PKD / HDAC5 signaling.