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1262858-66-1

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1262858-66-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1262858-66-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,8,5 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1262858-66:
(9*1)+(8*2)+(7*6)+(6*2)+(5*8)+(4*5)+(3*8)+(2*6)+(1*6)=181
181 % 10 = 1
So 1262858-66-1 is a valid CAS Registry Number.

1262858-66-1Relevant articles and documents

Synthesis of the Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor NB-360

Rueeger, Heinrich,Lueoend, Rainer,Machauer, Rainer,Veenstra, Siem J.,Holzer, Philipp,Hurth, Konstanze,Voegtle, Markus,Frederiksen, Mathias,Rondeau, Jean-Michel,Tintelnot-Blomley, Marina,Jacobson, Laura H.,Staufenbiel, Matthias,Laue, Grit,Neumann, Ulf

, p. 4677 - 4696 (2021/05/06)

Starting from lead compound 4, the 1,4-oxazine headgroup was optimized to improve potency and brain penetration. Focusing at the 6-position of the 5-amino-1,4-oxazine, the insertion of a Me and a CF3 group delivered an excellent pharmacological profile wi

1,4 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS

-

, (2012/07/28)

The present invention relates to 1,4 Oxazines of formula I having BACE 1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the prese

1,4 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS

-

, (2012/08/08)

The present invention provides 1,4 Oxazines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present

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