126312-79-6Relevant articles and documents
Enantioselective synthesis of a phenylalanine library containing alkyl groups on the aromatic moiety: Confirmation of stereostructure by X-ray analysis
Li, Tingyou,Tsuda, Yuko,Minoura, Katsuhiko,In, Yasuko,Ishida, Toshimasa,Lazarus, Lawrence H.,Okada, Yoshio
, p. 873 - 877 (2007/10/03)
Six phenylalanine analogues containing 2′-methyl-, 2′,6′-dimethyl-, 2′-ethyl-6′-methyl-, 2′-isopropyl-6′-methyl-, 2′,4′,6′-trimethyl-, and 3′,5′-dimethyl-L-phenylalanine were synthesized enantioselectively through asymmetric hydrogenation of acetamidoacrylate derivatives. Enzymatic digestion and X-ray analysis supported the L-configuration of the phenylalanine derivatives obtained.
Process for producing 2,6-disubstituted tyrosine
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, (2008/06/13)
A process for making 2,6-disubstituted tyrosine by the noble metal coupling of a disubstituted aromatic halide or diazonium salt with an amino-protected 2-aminoacrylic acid to form a (Z)-β-(disubstituted phenyl)-α-acylaminoacrylate, and asymmetrically hydrogenating the acrylate to produce the 2,6-disubstituted tyrosine.
