1263187-14-9 Usage
General Description
3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-acrylic acid ethyl ester is a chemical compound used in organic synthesis and pharmaceutical research. It is an ethyl ester derivative of acrylic acid that contains a boron-containing group. 3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-acrylic acid ethyl ester is commonly employed as a reagent in cross-coupling reactions to form carbon-carbon bonds, as well as in the synthesis of various pharmaceutical compounds. Its unique structure and properties make it a valuable tool in the development of new organic molecules with potential therapeutic applications. Additionally, its boron-containing group makes it useful in the formation of boron-containing materials, which have applications in materials science and catalysis.
Check Digit Verification of cas no
The CAS Registry Mumber 1263187-14-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,3,1,8 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1263187-14:
(9*1)+(8*2)+(7*6)+(6*3)+(5*1)+(4*8)+(3*7)+(2*1)+(1*4)=149
149 % 10 = 9
So 1263187-14-9 is a valid CAS Registry Number.
1263187-14-9Relevant articles and documents
Aliphatic α-Boryl-α-bromoketones: Synthesis and Reactivity
Ivon, Yevhen M.,Kuchkovska, Yuliya O.,Voitenko, Zoya V.,Grygorenko, Oleksandr O.
, p. 3367 - 3377 (2020/03/13)
A protocol for the preparation of α-boryl-α-bromoketones from alkenyl MIDA boronates was developed and applied to functionalized aliphatic derivatives. The reaction sequence included regioselective hydroxybromination of olefin moiety, followed by oxidation of alcohol group with Dess–Martin periodinane. The target trifunctional boronate-containing derivatives were obtained in up to 94 % yield over two steps starting from alkenyl MIDA boronates. In some cases, functional groups present in the substrate participated in the bromohydroxylation step via intramolecular nucleophilic attack at the bromonium cation leading to cyclic products. Additionally, the reactivity of aliphatic α-boryl-α-bromoketones was illustrated by nucleophilic substitution at the α-C atom and heterocyclization reactions.
