1263293-37-3

Basic information

• Product Name: 1-(2-hydroxyethyl)-8-[5-(4-methylpiperazin-1-yl)-2-trifluoromethoxyphenylamino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide fumarate
• CAS NO: 1263293-37-3
• Molecular Weight: 648.599
• Mol File: 1263293-37-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-hydroxyethyl)-8-[5-(4-methylpiperazin-1-yl)-2-trifluoromethoxyphenylamino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide fumarate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxyethyl)-8-[5-(4-methylpiperazin-1-yl)-2-trifluoromethoxyphenylamino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide fumarate(1263293-37-3)
• EPA Substance Registry System: 1-(2-hydroxyethyl)-8-[5-(4-methylpiperazin-1-yl)-2-trifluoromethoxyphenylamino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide fumarate(1263293-37-3)

Safety Data

• Hazardous Substances Data: 1263293-37-3(Hazardous Substances Data)

Upstream product

• 1034616-18-6 NMS-P937 
• 110-17-8 (2E)-but-2-enedioic acid 

Relevant articles and documents

PLK INHIBITOR SALTS

The present invention relates to novel crystalline, water-soluble salts of a plk inhibitor. Such crystal salts are for example L-tartrate, succinate, phosphate, mesylate, maleate, L-malate, hydrochloride, fumarate (half mole of counterion), fumarate, citrate (half mole of counterion), benzenesulfonate and L-aspartate (half mole of counterion). New crystal forms of the base as well as solvates and hydrates of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.