126330-90-3 Usage
Description
(R)-(+)-2-Piperazinecarboxylic acid dihydrochloride is an organic compound with the chemical formula C5H12N2O2·2HCl. It is a white solid and is known for its potential applications in the pharmaceutical and chemical industries due to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
(R)-(+)-2-Piperazinecarboxylic acid dihydrochloride is used as a starting material for the synthesis of (R)-enantiomers of anthramycin analogs, which are potential antiproliferative agents. These analogs have the potential to be developed into new drugs for the treatment of various types of cancer, as they can inhibit the proliferation of cancer cells.
Used in Chemical Synthesis:
(R)-(+)-2-Piperazinecarboxylic acid dihydrochloride is also employed in the preparation of piperazinemethanol chiral ligands. These ligands are crucial in the enantioselective borane reduction of aromatic ketones, ketimine, and oxime ether. The enantioselective reduction is an essential process in the synthesis of chiral compounds, which are vital in the pharmaceutical industry for the development of drugs with specific biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 126330-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,3,3 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 126330-90:
(8*1)+(7*2)+(6*6)+(5*3)+(4*3)+(3*0)+(2*9)+(1*0)=103
103 % 10 = 3
So 126330-90-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N2O2.2ClH/c8-5(9)4-3-6-1-2-7-4;;/h4,6-7H,1-3H2,(H,8,9);2*1H/t4-;;/m1../s1
126330-90-3Relevant articles and documents
SYNTHESIS AND CONVERSIONS OF PIPERAZINE-2-CARBOXYLIC ACID
Kutina, N. N.,Zhikhareva, G. P.,Anisimova, O. S.,Yakhontov, L. N.
, p. 693 - 696 (2007/10/02)
A method has been developed for the synthesis of methyl piperazinium-2-carboxylate dihydrochloride (overall yield 46percent) and piperazinium-2-carboxylic acid dihydrochloride (overall yield 36percent), from ethylene diamine through N,N'-di(trifluoroacetyl)ethylenediamine and methyl N,N'-di(trifluoroacetyl)piperazine-2-carboxylate.The N,N'-dinitroso derivatives were synthesized.
