126338-77-0 Usage
Description
Miramistin is a topical antiseptic with broad antimicrobial action, including activity against biofilms, and a clinical profile showing good tolerability. It is an antibacterial surfactant used in the stabilization of silver nanoparticles and various drug delivery systems.
Uses
Used in Wound Healing:
Miramistin is used as an antimicrobial component for the treatment of infected wounds of various genesis. It plays an important role in solving the problem of wound healing by providing powerful antimicrobial action without the side effects associated with antibiotics.
Used in Drug Delivery Systems:
Miramistin is used as a stabilizing agent for silver nanoparticles, which are employed in various drug delivery applications. This enhances the delivery, bioavailability, and therapeutic outcomes of the drugs.
Used in Antimicrobial Applications:
Miramistin is used as an antimicrobial component in the innovative substance of Chitosan-Miramistin Complex (CMC), which is effective against a wide range of microorganisms, including those that form biofilms. This makes it a valuable addition to the treatment of various infections and contributes to the development of new antimicrobial strategies.
History
An obscure antiseptic called miramistin, developed by the Soviet space program in the 1950s, may prove to have modern applications in the fight against harmful viruses and bacteria. It is available for clinical use in several prior Soviet bloc countries, but barely known outside of these countries and there is almost no mention of miramistin in the English literature.
Check Digit Verification of cas no
The CAS Registry Mumber 126338-77-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,3,3 and 8 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 126338-77:
(8*1)+(7*2)+(6*6)+(5*3)+(4*3)+(3*8)+(2*7)+(1*7)=130
130 % 10 = 0
So 126338-77-0 is a valid CAS Registry Number.
InChI:InChI=1/C26H46N2O/c1-4-5-6-7-8-9-10-11-12-13-17-21-26(29)27-22-18-23-28(2,3)24-25-19-15-14-16-20-25/h14-16,19-20H,4-13,17-18,21-24H2,1-3H3/p+1
126338-77-0Relevant articles and documents
N-(3-(Dimethyl benzyl ammonio)propyl)alkanamide chloride derivatives as corrosion inhibitors for mild steel in 1 M HCl solution: Experimental and theoretical investigation
Shaban, Samy M.
, p. 39784 - 39800 (2016)
The effects of N-(3-(dimethyl benzyl ammonio)propyl)lauramide chloride (DMBL), N-(3-(dimethyl benzyl ammonio)propyl)myristamide chloride (DMBM) and N-(3-(dimethyl benzyl ammonio)propyl)palmitamide chloride (DMBP) on the corrosion of mild carbon steel in acidic medium (1.0 M HCl) were investigated using weight loss and electrochemical measurements. The inhibition efficiency was found to be hydrophobicity- and temperature-dependent. Increasing the hydrophobic chain length increased the efficiency due to greater adsorption on the metal surface. The inhibition efficiency is directly proportional to the tested temperature. The electrochemical polarization study revealed that the tested cationic surfactants are mixed-type inhibitors. The Villamil adsorption isotherm is the better-fitted model for describing the adsorption process on the selected steel in 1.0 M HCl medium. The change in the free energy of adsorption of the synthesized cationic surfactants on the metal surface indicates that the adsorption process is chemisorption. Double-layer capacitance values obtained from electrochemical impedance spectroscopy decrease in the presence of the synthesized surfactant. Quantum chemical calculations support the experimental data and the adsorption on the metal surface.
ANTIVIRAL TREATMENT
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Page/Page column 27, (2021/09/11)
The present description relates to the use of myramistin, its derivatives and the forms thereof for treating or ameliorating infections caused by enveloped viruses, methods for preparing the compounds and pharmaceutical compositions containing such compounds. In particular the use of myramistin, its derivatives and forms for treating or ameliorating infections caused by coronaviruses. More particularly, the present description relates to the use of myramistin, its derivatives and forms thereof for treating or ameliorating Coronavirus disease 2019 (COVID-19).
