126339-09-1

Basic information

• Product Name: ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2
• Synonyms: ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2;PEPTIDE YY (3-36), PORCINE;PEPTIDE YY (3-36), HUMAN, SYNTHETIC >97%;peptide yy fragment 3-36 human;Peptide YY (3-36) (porcine, rat);M.W. 3980.44 C176H272N52O54;REF DUPL: H-Ala-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Ser-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2;Peptide YY (3-36) (canine, mouse, porcine, rat)
• CAS NO: 126339-09-1
• Molecular Formula: C176H272N52O54
• Molecular Weight: 0
• Product Categories: Neuropeptide Y and Peptide YY Peptides;Neuropeptide Y and Peptide YYNeuropeptides;Obesity Research;Peptide YY;Neurotransmission (Obesity);Neuropeptide Y (NPY ) receptor
• Mol File: 126339-09-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /lyophilized powder
• Storage Temp.: −20°C
• CAS DataBase Reference: ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2(CAS DataBase Reference)
• NIST Chemistry Reference: ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2(126339-09-1)
• EPA Substance Registry System: ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2(126339-09-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 126339-09-1(Hazardous Substances Data)

Usage

Description

ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2 is a 36 amino acid peptide known as Human Peptide YY (PYY). It is secreted by mucosal L cells in the distal ileum, colon, and rectum. The gene encoding PYY is located on human chromosome 17q21.1.

Uses

Used in Pharmaceutical Industry:
PYY is used as a therapeutic agent for various gastrointestinal and metabolic disorders due to its role in regulating gut motility, appetite, and energy balance. It has potential applications in the treatment of obesity, inflammatory bowel disease, and other related conditions.
Used in Research and Development:
PYY is utilized as a research tool for studying the mechanisms underlying gastrointestinal function, appetite regulation, and energy homeostasis. It helps researchers understand the complex interactions between the gut and the brain, as well as the role of PYY in these processes.
Used in Diagnostic Applications:
PYY can be used as a biomarker for diagnosing and monitoring certain gastrointestinal and metabolic disorders. Measuring PYY levels in patients can provide valuable information about the severity and progression of these conditions, guiding treatment decisions and patient management.
Used in Nutrition and Health Supplements:
PYY may be incorporated into nutritional supplements and health products aimed at promoting gut health, weight management, and overall well-being. These products could potentially help individuals maintain a healthy appetite, improve gut motility, and support energy balance.

Biochem/physiol Actions

Y2/Y5 Neuropeptide Y receptor agonist. Human peptide YY (PYY) has roles in energy homeostasis, food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes.