1264280-04-7

Basic information

• Product Name: (E)-4-(1,3-diphenyl-1H-pyrazol-4-yl)but-3-ene-2-one
• Synonyms: (E)-4-(1,3-diphenyl-1H-pyrazol-4-yl)but-3-ene-2-one
• CAS NO: 1264280-04-7
• Molecular Weight: 288.349
• Mol File: 1264280-04-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-4-(1,3-diphenyl-1H-pyrazol-4-yl)but-3-ene-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(1,3-diphenyl-1H-pyrazol-4-yl)but-3-ene-2-one(1264280-04-7)
• EPA Substance Registry System: (E)-4-(1,3-diphenyl-1H-pyrazol-4-yl)but-3-ene-2-one(1264280-04-7)

Safety Data

• Hazardous Substances Data: 1264280-04-7(Hazardous Substances Data)

Upstream product

• 21487-45-6 1,3-diphenyl-4-formylpyrazole 
• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 

Downstream Products

• 1422283-77-9 4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-1,3-diphenyl-1H-pyrazole 
• 1422283-67-7 (Z)-3-bromo-4-(1,3-diphenyl-1H-pyrazol-4-yl)but-3-en-2-one 

Relevant articles and documents

Organocatalyzed Asymmetric Conjugate Addition of Heteroaryl and Aryl Trifluoroborates: A Synthetic Strategy for Discoipyrrole D

Bis-heteroaryl or bis-aryl stereocenters were formed by an organocatalytic enantioselective conjugate addition using the respective trifluoroborate salts as nucleophiles. Control studies suggested that fluoride dissociation is necessary in the anhydrous conditions. This strategy is applicable to the synthesis of discoipyrrole D, an inhibitor of BR5 fibroblast migration.