1265907-75-2

Basic information

• Product Name: (3aR,4aS,8aR,9aR,E)-8a-methyl-5-methylidene-3-(4-fluorobenzylidene)decahydronaphtho[2,3-b]furan-2(3H)-one
• CAS NO: 1265907-75-2
• Molecular Weight: 326.411
• Mol File: 1265907-75-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3aR,4aS,8aR,9aR,E)-8a-methyl-5-methylidene-3-(4-fluorobenzylidene)decahydronaphtho[2,3-b]furan-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,4aS,8aR,9aR,E)-8a-methyl-5-methylidene-3-(4-fluorobenzylidene)decahydronaphtho[2,3-b]furan-2(3H)-one(1265907-75-2)
• EPA Substance Registry System: (3aR,4aS,8aR,9aR,E)-8a-methyl-5-methylidene-3-(4-fluorobenzylidene)decahydronaphtho[2,3-b]furan-2(3H)-one(1265907-75-2)

Safety Data

• Hazardous Substances Data: 1265907-75-2(Hazardous Substances Data)

Upstream product

• 470-17-7 isoalantolactone 
• 352-34-1 4-fluoro-1-iodobenzene 

Relevant articles and documents

Synthetic transformations of methylenelactones of eudesmanic type. Behavior of isoalantolactone under the conitions of heck reaction

By Heck reaction of isoalantolactone with aryl bromides or aryl iodides (3aR,4aS, 8aR,9aR,E)-3-arylmethylidene-8a-methyl-5- methylidenedecahydronaphtho[2,3-b]furan-2(3H)-ones and (4aS,8aR,9aS)-3- arylmethyl-8a-methyl-5-methylidene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b] furan-2(4H)-ones, products of the double bond shift, were synthesized. The yields of the arylation products depend on the nature of the catalytic system and on the structure of the aryl halide. The structures of (3aR,4aS,8aR,9aR,E)- 3-(3,4-dimethoxybenzylidene)-8amethyl-5-methylidenedecahydronaphtho[2,3-b] furan-2(3H)-one and (4aS,8aR,9aS)-3-(2-methylsulfanylbenzyl)-8amethyl-5- methylidene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one were proved by XRD analysis. Pleiades Publishing, Ltd., 2010.