126716-27-6

Basic information

• Product Name: methyl 2,5-di-O-benzoyl-3-fluoro-3-deoxy-α-D-ribofuranoside
• Synonyms: methyl 2,5-di-O-benzoyl-3-fluoro-3-deoxy-α-D-ribofuranoside
• CAS NO: 126716-27-6
• Molecular Weight: 374.366
• Mol File: 126716-27-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2,5-di-O-benzoyl-3-fluoro-3-deoxy-α-D-ribofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,5-di-O-benzoyl-3-fluoro-3-deoxy-α-D-ribofuranoside(126716-27-6)
• EPA Substance Registry System: methyl 2,5-di-O-benzoyl-3-fluoro-3-deoxy-α-D-ribofuranoside(126716-27-6)

Safety Data

• Hazardous Substances Data: 126716-27-6(Hazardous Substances Data)

Upstream product

• 126737-61-9 methyl 2-O-benzoyl-3-fluoro-3-deoxy-α-D-ribofuranoside 
• 98-88-4 benzoyl chloride 
• 532-32-1 sodium benzoate 
• 551929-57-8 Toluene-4-sulfonic acid (2S,3R,4R,5R)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-fluoro-2-methoxy-tetrahydro-furan-3-yl ester 
• 237410-13-8 ((2R,3S,4S,5S)-3-fluoro-4-hydroxy-5-methoxytetrahydrofuran-2-yl)methyl benzoate 
• 14645-35-3 methyl 3-fluoro-α-D-3-deoxy-arabinofuranoside 
• 26532-10-5 methyl 2,3-anhydro-α-D-lyxofuranoside 
• 7045-40-1 Methyl 3,5-O-Isopropylidene-α-D-xylofuranoside 
• 22834-71-5 Methyl-2-O-tosyl-α-D-xylofuranosid 
• 551929-55-6 methyl-[O³,O⁵-isopropylidene-O²-(toluene-4-sulfonyl)-α-D-xylofuranoside] 
• 14980-09-7 methyl 5-O-benzyl-3-fluoro-3-deoxy-α-D-arabino-furanoside 
• 14645-49-9 methyl 2,3-anhydro-5-O-benzyl-α-D-lyxofuranoside 
• 124939-87-3 methyl 5-O-benzyl-2-O-benzoyl-3-fluoro-3-deoxy-α-D-ribofuranoside 
• 126716-23-2 methyl 5-O-benzyl-2-O-tosyl-3-fluoro-3-deoxy-α-D-arabino-furanoside 

Downstream Products

• 75059-22-2 (2R,3S,4S,5R)-2-(6-amino-9H-purine-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol 
• 123402-20-0 3'-deoxy-3'-fluorocytidine 
• 123402-21-1 2-amino-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purine-6-one 
• 133776-13-3 C₂₃H₂₀FN₃O₆ 
• 112668-58-3 1-(2,5-di-O-benzoyl-3-deoxy-3-fluoro-β-D-ribofuranosyl)uracil 
• 133776-12-2 C₂₃H₁₉FN₂O₇ 
• 133776-14-4 C₂₆H₂₂FN₅O₇ 
• 112668-60-7 N6-benzoyl-9-(2'-O-benzoyl-3'-deoxy-3'-fluoro-β-D-ribofuranosyl)adenine 
• 133776-15-5 C₃₆H₄₂FN₅O₇ 
• 133776-16-6 C₃₆H₄₂FN₅O₇ 
• 25526-93-6 alovudine 
• 152711-06-3 Benzoic acid (2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 
• 152711-05-2 Benzoic acid (2R,3S,5S)-3-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 
• 152785-10-9 1,5-Di-O-benzoyl-2,3-dideoxy-3-fluoro-α-D-erythro-pentofuranose 

Relevant articles and documents

Design, synthesis and binding affinity of 3′-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands

Several 3′-fluoro analogues, 1a, 1b, and 1c of selective and potent adenosine A3 receptor agonist, Cl-IB-MECA were synthesized from D-xylose via highly regioselective opening of lyxo-epoxides, 8a and 8b with fluoride anion. Compared to the high binding affinity of Cl-IB-MECA to the A3 adenosine receptor, the corresponding 3′-fluoro derivative showed remarkably decreased binding affinity, indicating that 3′-hydroxyl group acts as hydrogen bonding acceptor, not hydrogen bonding donor like fluorine atom in binding to the A3 adenosine receptor.

Synthesis and antiviral and cytostatic properties of 3'-deoxy-3'-fluoro- and 2'-azido-3'-fluoro-2',3'-dideoxy-D-ribofuranosides of natural heterocyclic bases

A series of 3'-deoxy-3'-fluoro- and 2'-azido-2',3'-dideoxy-3'-fluoro-D-ribofuranosides of natural heterocyclic bases have been synthesized with the use of universal carbohydrate precursors, viz., 1-O-acetyl-2,5-di-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose