126799-87-9

Basic information

• Product Name: Benzene, 1-(azidomethyl)-2-bromo-
• CAS NO: 126799-87-9
• Molecular Formula: C7H6BrN3
• Molecular Weight: 212.049
• Mol File: 126799-87-9.mol
• Article Data: 36

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(azidomethyl)-2-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(azidomethyl)-2-bromo-(126799-87-9)
• EPA Substance Registry System: Benzene, 1-(azidomethyl)-2-bromo-(126799-87-9)

Safety Data

• Hazardous Substances Data: 126799-87-9(Hazardous Substances Data)

Upstream product

• 95-46-5 2-methylphenyl bromide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 143238-84-0 (2-bromophenyl)methyl methanesulfonate 
• 108-86-1 bromobenzene 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 18982-54-2 o-bromobenzyl alcohol 

Downstream Products

• 1245773-34-5 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(1-(2-bromobenzyl)-1H-1,2,3-triazol-4-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 
• 126800-11-1 1‐(2‐bromobenzyl)‐4‐phenyl‐1H‐1,2,3‐triazole 
• 1374747-14-4 C₁₆H₁₁BrClN₃O 
• 347146-14-9 ethyl 8-bromoquinoline-3-carboxylate 
• 126800-23-5 1-(2-bromobenzyl)-5-phenyl-1H-1,2,3-triazole 
• 947395-59-7 1-(azidomethyl)-2-(phenylethynyl)benzene 
• 1357271-91-0 C₃₇H₅₄BrN₃O 
• 1295479-59-2 C₂₅H₂₈BrF₂N₇O 
• 1343495-63-5 methyl 2-{[1-(2-bromobenzyl)-1H-1,2,3-triazol-4-yl]methyl}-5-(2-hydroxyethyl)-1,2,5-thiadiazepane-3-carboxylate 1,1-dioxide 

Relevant articles and documents

Synthesis of novel benzimidazole and benzothiazole derivatives bearing a 1,2,3-triazole ring system and their acetylcholinesterase inhibitory activity

A series of 20 novel benzimidazole and benzothiazole derivatives linked to a 1,2,3-triazole ring system was synthesised, characterised and evaluated for in vitro acetylcholinesterase (AChE) inhibitory activity. Several copper catalysts and solvents were screened to establish the optimal conditions for the preparation of the target compounds. Three different linkers were used to optimise the enzyme inhibitory effect. Out of the 20 compounds, 13 showed some AChE inhibition. The most potent compound, which showed 84% inhibition at 100 μM, contained a 1-(2-fluorobenzyl)-1,2,3-triazole linked to a benzimidazole group. A docking simulation study showed that the most active compound bound preferentially to the catalytic anionic subsite of the AChE enzyme.

Synthesis of 1,2,3-triazole benzophenone derivatives and evaluation of in vitro sun protection, antioxidant properties, and antiproliferative activity on HT-144 melanoma cells

Benzophenones display several biological activities, including antioxidant, anticancer, and photoprotective. Furthermore, antioxidants can minimize both ultraviolet absorption and tumor development. In the present investigation, a series of twenty-six 1,2

Synthesis of 1,2,3,triazole modified analogues of hydrochlorothiazide via click chemistry approach and in-vitro α-glucosidase enzyme inhibition studies

The current study was aimed to discover potent inhibitors of α-glucosidase enzyme. A 25 membered library of new 1,2,3-triazole derivatives of hydrochlorothiazide (1) (HCTZ, a diuretic drug also being used for the treatment of high blood pressure) was synt