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1268267-77-1

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1268267-77-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1268267-77-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,8,2,6 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1268267-77:
(9*1)+(8*2)+(7*6)+(6*8)+(5*2)+(4*6)+(3*7)+(2*7)+(1*7)=191
191 % 10 = 1
So 1268267-77-1 is a valid CAS Registry Number.

1268267-77-1Relevant articles and documents

Synthesis and antiplasmodial activity of bicyclic dioxanes as simplified dihydroplakortin analogues

Gemma, Sandra,Kunjir, Sanil,Sanna Coccone, Salvatore,Brindisi, Margherita,Moretti, Vittoria,Brogi, Simone,Novellino, Ettore,Basilico, Nicoletta,Parapini, Silvia,Taramelli, Donatella,Campiani, Giuseppe,Butini, Stefania

supporting information; experimental part, p. 5949 - 5953 (2011/10/09)

Here we report the synthesis and evaluation of antiplasmodial activity of a novel series of bicyclic peroxides inspired by the marine natural compound dihydroplakortin. We developed a synthetic strategy leading to the dihydroplakortin-related peroxides in only a few steps. The in vitro antiplasmodial potency of the peroxides was similar to, or greater than, that of the reference natural compound, and structure-activity relationship studies revealed several key structural requirements for activity and potency.

Substituted pyrimidine compositions and methods of use

-

, (2008/06/13)

Substituted pyrimidines that have the general structure: in which the symbol R1represents a C1-C6alkyl, C1-C6alkoxy or halogen atom; R2represents a phenyl group, substituted phenyl group, benzyl moiety, substituted benzyl moiety, C3-C7cycloalkyl, or substituted C3-C7cycloalkyl; R3represents a hydrogen or C1-C6alkyl group, R4represents —H, —OH, —N3or —NHCOCH3; and R5represents H are provided. These compounds have activity as inhibitors of phospholipase A2, and are useful in treating disorders mediated by phospholipase A2.

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