1268279-39-5Relevant articles and documents
An organocatalytic rearrangement of 2-(N-alkyl-/aryl-)amino-4-oxo-4H-1- benzopyran-3-carbaldehyde
Maiti, Sourav,Panja, Suman Kalyan,Bandyopadhyay, Chandrakanta
, p. 1946 - 1948 (2011)
2-(Arylamino)-4-oxo-4H-1-benzopyran-3-carbaldehyde rearranges to 4-oxo-4H-1-benzopyran-3-carbanilide when treated with glycine in the presence of formalin, but under similar conditions 2-(alkylamino)-4-oxo-4H-1-benzopyran-3- carbaldehyde rearranges to 3-a
Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry
Cagide,Silva,Reis,Gaspar,Borges,Gomes,Low
, p. 2832 - 2835 (2015/02/19)
The discovery of potent and selective monoamine oxidase-B inhibitors for the management of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases is still a challenging endeavor. Herein, we report the discovery of two new classes of poten
Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors
Gaspar, Alexandra,Reis, Joana,Fonseca, Andre,Milhazes, Nuno,Vina, Dolores,Uriarte, Eugenio,Borges, Fernanda
experimental part, p. 707 - 709 (2011/03/18)
Monoamine oxidase (MAO) is an enzyme, present in mammals in two isoforms MAO-A and MAO-B. These isoforms have a crucial role in neurotransmitters metabolism, representing an attractive drug target in the therapy of neurodegenerative diseases (MAO-B) and d