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1268618-16-1

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1268618-16-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1268618-16-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,8,6,1 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1268618-16:
(9*1)+(8*2)+(7*6)+(6*8)+(5*6)+(4*1)+(3*8)+(2*1)+(1*6)=181
181 % 10 = 1
So 1268618-16-1 is a valid CAS Registry Number.

1268618-16-1Downstream Products

1268618-16-1Relevant articles and documents

Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells

Powell, Jonathan,Mota, Filipa,Steadman, David,Soudy, Christelle,Miyauchi, Jeremy T.,Crosby, Stuart,Jarvis, Ashley,Reisinger, Tifelle,Winfield, Natalie,Evans, Graham,Finniear, Aled,Yelland, Tamas,Chou, Yi-Tai,Chan, A.W. Edith,O'Leary, Andrew,Cheng, Lili,Liu, Dan,Fotinou, Constantina,Milagre, Carla,Martin, John F.,Jia, Haiyan,Frankel, Paul,Djordjevic, Snezana,Tsirka, Stella E.,Zachary, Ian C,Selwood, David L.

, p. 4135 - 4154 (2018/05/23)

We report the design, synthesis, and biological evaluation of some potent small-molecule neuropilin-1 (NRP1) antagonists. NRP1 is implicated in the immune response to tumors, particularly in Treg cell fragility, required for PD1 checkpoint blockade. The d

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