1268718-04-2Relevant articles and documents
Inhibition of secreted phospholipases A2 by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations
Mouchlis, Varnavas D.,Magrioti, Victoria,Barbayianni, Efrosini,Cermak, Nathan,Oslund, Rob C.,Mavromoustakos, Thomas M.,Gelb, Michael H.,Kokotos, George
experimental part, p. 735 - 743 (2011/03/18)
Group IIA secreted phospholipase A2 (GIIA sPLA2) is a member of the mammalian sPLA2 enzyme family and is associated with various inflammatory conditions. In this study, the synthesis of 2-oxoamides based on α-amino acids a