1269183-17-6

Basic information

• Product Name: 6‐(trifluoromethyl)phenanthridine
• Synonyms: 6‐(trifluoromethyl)phenanthridine
• CAS NO: 1269183-17-6
• Molecular Weight: 247.219
• Mol File: 1269183-17-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 6‐(trifluoromethyl)phenanthridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6‐(trifluoromethyl)phenanthridine(1269183-17-6)
• EPA Substance Registry System: 6‐(trifluoromethyl)phenanthridine(1269183-17-6)

Safety Data

• Hazardous Substances Data: 1269183-17-6(Hazardous Substances Data)

Upstream product

• 2926-29-6 Langlois reagent 
• 3128-77-6 2-isocyanobiphenyl 

Relevant articles and documents

Silver-Catalyzed Tandem Trifluoromethylation and Cyclization of Aryl Isonitriles with the Langlois Reagent

A mild and efficient procedure for the silver-catalyzed tandem trifluoromethylation and cyclization of aryl isonitriles with the Langlois reagent (sodium triflinate) is developed. A series of trifluoromethylated phenanthridines is prepared in moderate to good yields from a cheap and stable trifluoromethyl source.

Visible-light-induced tandem radical addition-cyclization of 2-aryl phenyl isocyanides catalysed by recyclable covalent organic frameworks

A visible-light-induced tandem radical addition-cyclization sequence via 2-aryl phenyl isocyanides as the starting material and two-dimensional covalent organic frameworks (2D-COFs) as the photocatalyst was developed, delivering multifarious 6-substituted phenanthridines in high yields. Benefitting from the utilization of a heterogeneous photocatalyst, this protocol features easy catalyst separation and excellent recyclability. A negligible loss of the catalytic activity was observed after multiple runs. High practicability of this protocol was further demonstrated by continuous flow experiments.

Transition Metal-Free Oxidative Radical Decarboxylation/Cyclization for the Construction of 6-Alkyl/Aryl Phenanthridines

A radical cascade decarboxylation/cyclization of 2-isocyanobiphenyls with aliphatic carboxylic acids as well as aromatic carboxylic acids under the transition metal-free conditions was reported. This process, which included formation of two new C-C bonds and cleavage of C-COOH bonds, afforded a novel and environmentally friendly approach to producing 6-alkyl/aryl phenanthridines with moderate to good yields.