1269195-05-2 Usage
Description
1-benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate is a complex organic compound with a unique molecular structure. It is characterized by a pyrrolidine ring with a benzyl and methyl group at the 1st and 2nd positions, respectively. The 4th position of the pyrrolidine ring is connected to a 4-bromoisoindoline-2-carbonyloxy group, which is derived from a 4-bromoisoindoline-2-carboxylic acid. 1-benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate also features two carboxylate groups, making it a dicarboxylate. This intricate structure endows the compound with potential applications in various fields, particularly in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
1-benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate is used as a key intermediate in the synthesis of drug-like molecules. Its unique structure allows it to be a valuable building block for the development of new pharmaceutical compounds with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 1-benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate serves as an important compound for studying various chemical reactions and mechanisms. Its complex structure provides opportunities for exploring new synthetic routes and reaction conditions, which can lead to the discovery of novel chemical processes and products.
Used in the Aryl Halide Chemistry Informer Library:
1-benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate is an Informer compound X8 of the Aryl Halide Chemistry Informer Library developed by chemists at Merck & Co., Inc. This library contains 18 drug-like molecules representative of those encountered in complex synthesis. By screening new reactions against the Informer Library, chemists can directly compare and analyze a reaction's successes and shortcomings among different methods and various research teams. It may also be used to facilitate deeper method development for performance or utility.
Check Digit Verification of cas no
The CAS Registry Mumber 1269195-05-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,9,1,9 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1269195-05:
(9*1)+(8*2)+(7*6)+(6*9)+(5*1)+(4*9)+(3*5)+(2*0)+(1*5)=182
182 % 10 = 2
So 1269195-05-2 is a valid CAS Registry Number.
1269195-05-2Relevant articles and documents
Synthesis of vaniprevir (MK-7009): Lactamization to prepare a 22-membered macrocycle
Song, Zhiguo J.,Tellers, David M.,Journet, Michel,Kuethe, Jeffrey T.,Lieberman, David,Humphrey, Guy,Zhang, Fei,Peng, Zhihui,Waters, Marjorie S.,Zewge, Daniel,Nolting, Andrew,Zhao, Dalian,Reamer, Robert A.,Dormer, Peter G.,Belyk, Kevin M.,Davies, Ian W.,Devine, Paul N.,Tschaen, David M.
, p. 7804 - 7815 (2011/12/14)
Development of a practical synthesis of MK-7009, a 22-membered macrocycle, is described. A variety of ring-closing strategies were evaluated, including ring-closing metathesis, intermolecular palladium-catalyzed cross-couplings, and macrolactamization. Ri
