1269417-09-5

Basic information

• Product Name: 2-(2-chloro-2,2-dideuteroethyl)-1,3-dioxolane
• Synonyms: 2-(2-chloro-2,2-dideuteroethyl)-1,3-dioxolane
• CAS NO: 1269417-09-5
• Molecular Weight: 138.562
• Mol File: 1269417-09-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-chloro-2,2-dideuteroethyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chloro-2,2-dideuteroethyl)-1,3-dioxolane(1269417-09-5)
• EPA Substance Registry System: 2-(2-chloro-2,2-dideuteroethyl)-1,3-dioxolane(1269417-09-5)

Safety Data

• Hazardous Substances Data: 1269417-09-5(Hazardous Substances Data)

Upstream product

• 1269417-07-3 C₁₂H₁₄⁽²⁾HClO₃S 

Relevant articles and documents

Iterative stereospecific reagent-controlled homologation using a functionalized α-chloroalkyllithium: Synthesis of cyclic targets related to epibatidine

Enantioenriched 1-chloro-2-(1,3-dioxolan-2-yl)ethyllithium was generated by PhLi initiated sulfoxide-ligand exchange and deployed in situ for sequential double stereospecific reagent-controlled homologation (StReCH) of B-(2-chloro-pyrid-5-yl) pinacol boronate. This process afforded highly functionalized contiguous stereodiad motifs (typically, % ee ≥ 98%, dr ≥ 85:15) amenable to subsequent annulative transformations as demonstrated by the concise synthesis (5-7 steps) of cyclic adducts related to the analgesic alkaloid epibatidine.