127-68-4 Usage
Description
Sodium 3-nitrobenzenesulphonate, also known as sodium 3-nitrobenzenesulfonate, is a chemical compound with the formula C6H4NO3SNa. It is a solid substance that is used as a reagent in various chemical reactions and has applications in different industries.
Uses
Used in Pharmaceutical Industry:
Sodium 3-nitrobenzenesulphonate is used as a reagent for the synthesis of azetidinyl ketolides, which are important for the treatment of susceptible and multidrug-resistant community-acquired respiratory tract infections. Its role in the synthesis process contributes to the development of effective medications to combat various respiratory infections.
Used in Chemical Synthesis:
As a solid reagent, sodium 3-nitrobenzenesulphonate is utilized in various chemical reactions, enabling the production of different compounds with specific properties and applications. Its versatility in chemical synthesis makes it a valuable component in the development of new materials and products across various industries.
Flammability and Explosibility
Nonflammable
Check Digit Verification of cas no
The CAS Registry Mumber 127-68-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127-68:
(5*1)+(4*2)+(3*7)+(2*6)+(1*8)=54
54 % 10 = 4
So 127-68-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H5NO5S/c8-7(9)5-2-1-3-6(4-5)13(10,11)12/h1-4H,(H,10,11,12)/p-1
127-68-4Relevant articles and documents
Method for preparing sodium 3-nitrobenzene sulfonate and derivative thereof through chlorosulfonic acid sulfonation
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Paragraph 0046-0059; 0062-0066, (2019/01/07)
The invention discloses a method for preparing sodium 3-nitrobenzene sulfonate and a derivative thereof through chlorosulfonic acid sulfonation. The method comprises the following steps: 1) putting anitrobenzene raw material and chlorosulfonic acid into a reaction container, heating to 90-150 DEG C, keeping the temperature, carrying out a sulfonation reaction, and discharging a hydrogen chloridegas generated in the reaction process outside the reaction system in time, wherein the mole ratio of the nitrobenzene raw material to the chlorosulfonic acid is 1:(0.4-0.6); 2) carrying out aftertreatment on the reaction liquid obtained in the step 1) by using soda, thereby obtaining the sodium 3-nitrobenzene sulfonate or the derivative thereof. By adopting the method, a reverse thinking mode is adopted, the amount of the chlorosulfonic acid is reduced till being smaller than that of the nitrobenzene, and then the small amount of the chlorosulfonic acid can be converted by using the excessiveamount of the nitrobenzene; therefore, the method disclosed by the invention has no problem of treating residual chlorosulfonic acid; in addition, the excessive nitrobenzene can be easily recycled andcirculated, the hydrogen chloride as a byproduct can be also easily separated and recycled.