127041-69-4

Basic information

• Product Name: benzyl (2S,3R)-3-hydroxyhex-5-en-2-ylcarbamate
• Synonyms: benzyl (2S,3R)-3-hydroxyhex-5-en-2-ylcarbamate
• CAS NO: 127041-69-4
• Molecular Weight: 249.31
• Mol File: 127041-69-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: benzyl (2S,3R)-3-hydroxyhex-5-en-2-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2S,3R)-3-hydroxyhex-5-en-2-ylcarbamate(127041-69-4)
• EPA Substance Registry System: benzyl (2S,3R)-3-hydroxyhex-5-en-2-ylcarbamate(127041-69-4)

Safety Data

• Hazardous Substances Data: 127041-69-4(Hazardous Substances Data)

Upstream product

• 82353-55-7 benzyl (S)-1-oxopropan-2-ylcarbamate 
• 1730-25-2 allylmagnesium bromide 
• 107-37-9 allyltrichlorosilane 
• 501-53-1 benzyl chloroformate 
• 1034089-14-9 (2S,3SR)-2-{[(tert-butoxy)carbonyl]amino}hex-5-en-3-ol 
• 106-95-6 allyl bromide 
• 28819-05-8 (S)-2-benzyloxycarbonylamino-propionic acid methyl ester 
• 1337862-57-3 (S)-benzyl 3-oxohex-5-en-2-ylcarbamate 
• 24850-33-7 allyltributylstanane 
• 762-72-1 allyl-trimethyl-silane 
• 114744-83-1 (S)-benzyl (1-(N,O-dimethylhydroxylamine)-1-oxopropan-2-yl)carbamate 

Downstream Products

• 924627-17-8 benzyl ((1S)-2-([tert-butyl(dimethyl)silyl]oxy)-1-methylpenta-4-en-1-yl)carbamate 
• 1337862-70-0 (2S,3R)-benzyl 3-(tert-butyldimethylsilyloxy)-2-methyl-5-oxopyrrolidine-1-carboxylate 

Relevant articles and documents

A facile approach to trans-4,5-pyrrolidine lactam and application in the synthesis of nemonapride and streptopyrrolidine

An efficient approach to trans-4-hydroxylpyrrolidine lactams 1 starting from amino acid is described. The utility of this method has been demonstrated in the synthesis of antipsychotic nemonapride 3 and antiangiogenic streptopyrrolidine 4. Compared four s

CYCLIC AMINE COMPOUND

A compound represented by the formula (I) or a salt thereof: (I) wherein the ring A represents a 5- to 8-membered ring which may have additional substituent besides R6, R7 and R8; R1 represents an electron-attracting group; R2, R3, R4 and R5 independently represent a hydrogen atom, a halogen atom, a group attached through a carbon atom, a group attached through a nitrogen atom, a group attached through an oxygen group, or a group attached through a sulfur atom; R6 represents a halogen atom, a group attached through a carbon atom, a group attached through a nitrogen atom, a group attached through an oxygen group, or a group attached through a sulfur atom, and R7 represents a cyano group, a nitro group, an acyl group which may have a substituent, a carboxyl group which may be esterified or amidated, or a hydrocarbon group which may have a substituent, or R6 and R7 together with a carbon atom to which they are attached may form a ring which may have a substituent; and R8 represents a hydrogen atom, a halogen atom, a group attached through a carbon atom, a group attached through an oxygen atom, or a group attached through a sulfur atom. The compound or salt has an excellent androgen receptor modulating effect, and is useful for the prevention/treatment of hypogonadism, partial androgen deficiency in aging male, decline in physical strength, cachexia, osteoporosis and the like.

Diastereoselective addition of allyl reagents to variously N-monoprotected and N,N-diprotected L-alaninals

Diastereoselective C3-elongation processes of N-Boc-, N-Z-, N-Bn-N-Boc-, and N-Bn-N-Z-L-alaninals (Boc = 'BuOCO, Z = PhCH2OCO, Bn = PhCH2) using various allyl reagents, such as allyl bromide in the presence of Zn/aqueous N