127049-87-0 Usage
Description
3-BroMo-2,6-dichloro-1-Methylbenzene, also known as 1-Bromo-2,4-dichloro-3-methylbenzene, is an organic compound with a molecular structure featuring a benzene ring substituted with a bromine atom, two chlorine atoms, and a methyl group. It is characterized by its chemical stability and reactivity, making it a versatile compound for various applications.
Uses
Used in Pharmaceutical Industry:
3-BroMo-2,6-dichloro-1-Methylbenzene is used as an intermediate in the synthesis of cycloalkyl lactam derivatives, which serve as 11β-HSD1 inhibitors. These inhibitors play a crucial role in the treatment of various metabolic disorders and conditions related to the dysregulation of cortisol levels, such as type 2 diabetes, obesity, and Cushing's syndrome. The compound's unique structure allows for the development of potent and selective inhibitors, contributing to the advancement of therapeutic options in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 127049-87-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,0,4 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 127049-87:
(8*1)+(7*2)+(6*7)+(5*0)+(4*4)+(3*9)+(2*8)+(1*7)=130
130 % 10 = 0
So 127049-87-0 is a valid CAS Registry Number.
127049-87-0Relevant articles and documents
N-SULFONYL BENZAMIDE DERIVATIVE WITH HETEROCYCLIC SUBSTITUENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF
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Paragraph 0162; 0163, (2019/01/04)
The present invention discloses an N-sulfonyl benzamide derivative with a heterocyclic substituent, and a preparation method therefor and a pharmaceutical application thereof. More specifically, the invention discloses a compound represented by formula (II) or a pharmaceutically acceptable salt, stereoisomer, solvent compound, or prodrug thereof, and a preparation method therefor and an application thereof. Refer to the specification for definitions of each group in the formula.
Process for producing 4-benzoyl-5-hydroxypyrazoles
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, (2008/06/13)
A process for producing a 4-benzoyl-5-hydroxylpyrazole of the formula III: STR1 which comprises reacting carbon monoxide and a 5-hydroxypyrazole of the formula II: STR2 to a substituted benzene of the formula I: STR3 wherein X is a bromine atom, an iodine atom or a diazonium tetrafluoroboron salt group, in the presence of a base and a catalyst of Group VIII of the Periodic Table.
