1270932-01-8

Basic information

• Product Name: 3,6-dimethyl-2-methoxy-5-hydroxydecyl-p-benzo-quinone
• CAS NO: 1270932-01-8
• Molecular Weight: 322.445
• Mol File: 1270932-01-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,6-dimethyl-2-methoxy-5-hydroxydecyl-p-benzo-quinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-dimethyl-2-methoxy-5-hydroxydecyl-p-benzo-quinone(1270932-01-8)
• EPA Substance Registry System: 3,6-dimethyl-2-methoxy-5-hydroxydecyl-p-benzo-quinone(1270932-01-8)

Safety Data

• Hazardous Substances Data: 1270932-01-8(Hazardous Substances Data)

Upstream product

• 3669-80-5 11-hydroxyundecanoic acid 
• 2913-45-3 2-methoxy-3,6-dimethyl-1,4-benzoquinone 

Relevant articles and documents

Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria

Analogues of mitoQ and idebenone were synthesized to define the structural elements that support oxygen consumption in the mitochondrial respiratory chain. Eight analogues were prepared and fully characterized, then evaluated for their ability to support oxygen consumption in the mitochondrial respiratory chain. While oxygen consumption was strongly inhibited by mitoQ analogues 2-4 in a chain length-dependent manner, modification of idebenone by replacement of the quinone methoxy groups by methyl groups (analogues 6-8) reduced, but did not eliminate, oxygen consumption. Idebenone analogues 6-8 also displayed significant cytoprotective properties toward cultured mammalian cells in which glutathione had been depleted by treatment with diethyl maleate.